Dilemmas in the diagnosis of acute community-acquired bacterial meningitis

Rapid diagnosis and treatment of acute community-acquired bacterial meningitis reduces mortality and neurological sequelae, but can be delayed by atypical presentation, assessment of lumbar puncture safety, and poor sensitivity of standard diagnostic microbiology. Thus, diagnostic dilemmas are commo...

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Bibliographic Details
Published in:	The Lancet (British edition) Vol. 380; no. 9854; pp. 1684 - 1692
Main Authors:	Brouwer, Matthijs C, Thwaites, Guy E, Tunkel, Allan R, van de Beek, Diederik
Format:	Journal Article
Language:	English
Published:	Kidlington Elsevier Ltd 10.11.2012 Elsevier Elsevier Limited
Subjects:	Acute Disease Age Anti-Bacterial Agents - therapeutic use Antibiotics Autoimmune diseases Bacteria Bacterial diseases Bacterial diseases of the nervous system. Bacterial myositis Biological and medical sciences Biomarkers - blood Biomarkers - cerebrospinal fluid brain cerebrospinal fluid clinical examination Community-Acquired Infections - cerebrospinal fluid Community-Acquired Infections - diagnosis Community-Acquired Infections - drug therapy complications (disease) Decision Support Techniques Diagnosis, Differential Disease Family medical history Fever General aspects Headaches HIV Human bacterial diseases Human immunodeficiency virus Humans image analysis Immune status Infectious diseases Internal Medicine Medical History Taking - methods Medical sciences Meningitis Meningitis, Bacterial - cerebrospinal fluid Meningitis, Bacterial - diagnosis Meningitis, Bacterial - drug therapy Microbiology mortality patients Physical Examination - methods Physicians prediction Prediction models Spinal Puncture - methods Streptococcus infections Tomography, X-Ray Computed Infection Medicine Nervous system diseases Community acquired infection Bacterial meningitis Acute Bacteriosis Diagnosis
ISSN:	0140-6736, 1474-547X, 1474-547X
Online Access:	Get full text
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