Experimental Infection of Mink with SARS-COV-2 Omicron Variant and Subsequent Clinical Disease

We report an experimental infection of American mink with SARS-CoV-2 Omicron variant and show that mink remain positive for viral RNA for days, experience clinical signs and histopathologic changes, and transmit the virus to uninfected recipients. Preparedness is crucial to avoid spread among mink a...

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Bibliographic Details
Published in:Emerging infectious diseases Vol. 28; no. 6; pp. 1286 - 1288
Main Authors: Virtanen, Jenni, Aaltonen, Kirsi, Kegler, Kristel, Venkat, Vinaya, Niamsap, Thanakorn, Kareinen, Lauri, Malmgren, Rasmus, Kivelä, Olga, Atanasova, Nina, Österlund, Pamela, Smura, Teemu, Sukura, Antti, Strandin, Tomas, Dutra, Lara, Vapalahti, Olli, Nordgren, Heli, Kant, Ravi, Sironen, Tarja
Format: Journal Article
Language:English
Published: United States U.S. National Center for Infectious Diseases 01.06.2022
Centers for Disease Control and Prevention
Subjects:
animals
Antigens
Coronaviruses
COVID-19
Disease transmission
Edema
Experimental Infection of Mink with SARS-COV-2 Omicron Variant and Subsequent Clinical Disease
Farms
Human populations
Hyperplasia
Infections
Laboratory animals
Medical research
Medicine, Experimental
mink
Neutrophils
Research Letter
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
Viruses
Zoonoses
Finland
COVID-19
models
SARS-CoV-2
viruses
severe acute respiratory syndrome coronavirus 2
Finland
zoonoses
coronavirus disease
mink
animals
respiratory infections
ISSN:1080-6040, 1080-6059, 1080-6059
Online Access:Get full text
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Description
Summary:We report an experimental infection of American mink with SARS-CoV-2 Omicron variant and show that mink remain positive for viral RNA for days, experience clinical signs and histopathologic changes, and transmit the virus to uninfected recipients. Preparedness is crucial to avoid spread among mink and spillover to human populations.
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ISSN:1080-6040
1080-6059
1080-6059
DOI:10.3201/eid2806.220328