Meta-analysis of genome-wide association data identifies two loci influencing age at menarche

André Uitterlinden and colleagues report loci at 9q31.2 and LIN28B associated with age at menarche from a meta-analysis of genome-wide association studies including 17,510 females from eight different population-based cohorts. We conducted a meta-analysis of genome-wide association data to detect ge...

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Vydané v:	Nature genetics Ročník 41; číslo 6; s. 648 - 650
Hlavní autori:	Perry, John R B, Stolk, Lisette, Franceschini, Nora, Lunetta, Kathryn L, Zhai, Guangju, McArdle, Patrick F, Smith, Albert V, Aspelund, Thor, Bandinelli, Stefania, Boerwinkle, Eric, Cherkas, Lynn, Eiriksdottir, Gudny, Estrada, Karol, Ferrucci, Luigi, Folsom, Aaron R, Garcia, Melissa, Gudnason, Vilmundur, Hofman, Albert, Karasik, David, Kiel, Douglas P, Launer, Lenore J, van Meurs, Joyce, Nalls, Michael A, Rivadeneira, Fernando, Shuldiner, Alan R, Singleton, Andrew, Soranzo, Nicole, Tanaka, Toshiko, Visser, Jenny A, Weedon, Michael N, Wilson, Scott G, Zhuang, Vivian, Streeten, Elizabeth A, Harris, Tamara B, Murray, Anna, Spector, Tim D, Demerath, Ellen W, Uitterlinden, André G, Murabito, Joanne M
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	New York Nature Publishing Group US 01.06.2009 Nature Publishing Group
Predmet:	Adolescent Age Age Factors Agriculture Animal Genetics and Genomics Biological and medical sciences Biomedical and Life Sciences Biomedicine Body Mass Index brief-communication Cancer Research Child Chromosome Mapping Chromosomes Chromosomes, Human, Pair 6 - genetics Chromosomes, Human, Pair 8 - genetics Chromosomes, Human, Pair 9 - genetics Complications and side effects DNA-Binding Proteins - genetics Female Females Fundamental and applied biological sciences. Psychology Gene Function Genetic aspects Genetic variance Genetic Variation Genetics Genetics of eukaryotes. Biological and molecular evolution Genome-Wide Association Study Genomics Human Genetics Humans Menarche Menarche - genetics Menstruation Meta-analysis Meta-Analysis as Topic Obesity Polymorphism, Single Nucleotide RNA-Binding Proteins Sexual Maturation - genetics Studies Australia Identification Association Locus Age Metaanalysis
ISSN:	1061-4036, 1546-1718, 1546-1718
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