Cell fusion enhances energy metabolism of mesenchymal tumor hybrid cells to sustain their proliferation and invasion

Background Cell-to-cell fusion is emerging as a key element of the metastatic process in various cancer types. We recently showed that hybrids made from the spontaneous merging of pre-malignant (IMR90 E6E7, i.e. E6E7) and malignant (IMR90 E6E7 RST, i.e. RST) mesenchymal cells recapitulate the main f...

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Bibliographic Details
Published in:	BMC cancer Vol. 21; no. 1; pp. 1 - 12
Main Authors:	Brito, Ariadna, Merle, Candice, Lagarde, Pauline, Faustin, Benjamin, Devin, Anne, Lartigue, Lydia, Chibon, Frederic
Format:	Journal Article
Language:	English
Published:	London BioMed Central 28.07.2021 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	AICAR AMP AMPK Bioenergetics Biomedical and Life Sciences Biomedicine Biosynthesis Cancer Cancer cells Cancer Research Cell division Cell fusion Cell growth Cell hybridization Cell proliferation Energy Energy metabolism Environmental conditions Forecasts and trends Gene expression Genomes Glucose Glycolysis Growth Health aspects Health Promotion and Disease Prevention Hybrids Invasion Invasiveness Kinases Life Sciences Medicine/Public Health Mesenchyme Metabolism Metastases Metastasis Oncology Phosphorylation Physiological aspects Protein kinase Respiration Sarcoma Surgical Oncology Tumors France AMPK Energy metabolism AICAR Cell fusion Invasion
ISSN:	1471-2407, 1471-2407
Online Access:	Get full text
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