Absolute risk-based versus individualized benefit approaches for determining statin eligibility in primary prevention of cardiovascular diseases in Chinese populations: A modeling study

Current guidelines for statin use in primary prevention of cardiovascular disease (CVD) predominantly rely on absolute 10-year CVD risk scores. However, this approach may not adequately capture heterogeneity in the potential benefit of low-density lipoprotein cholesterol (LDL-C) reduction. This stud...

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Bibliographic Details
Published in:	PLoS medicine Vol. 22; no. 7; p. e1004556
Main Authors:	Liu, Qiuping, Gong, Chao, Zhou, Tianjing, Zhang, Minglu, Liu, Xiaofei, Tang, Xun, Gao, Pei
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 22.07.2025 Public Library of Science (PLoS)
Subjects:	Adult Aged Aged, 80 and over Analysis and chemistry Biology and Life Sciences Blood Cardiovascular agents Cardiovascular disease Cardiovascular diseases Cardiovascular Diseases - blood Cardiovascular Diseases - epidemiology Cardiovascular Diseases - prevention & control China - epidemiology Cholesterol Cholesterol, LDL - blood Decision making Diabetes Diabetes mellitus Discordance Disease prevention Dosage and administration East Asian People Efficiency Female Health aspects Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Lipids Lipoproteins Longitudinal Studies Low density lipoprotein Male Medicine and Health Sciences Middle Aged Population Population studies Prevention Primary Prevention - methods Review boards Risk Assessment Risk factors Statins China
ISSN:	1549-1676, 1549-1277, 1549-1676
Online Access:	Get full text
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