Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information

Posttraumatic stress disorder (PTSD) is heritable and a potential consequence of exposure to traumatic stress. Evidence suggests that a quantitative approach to PTSD phenotype measurement and incorporation of lifetime trauma exposure (LTE) information could enhance the discovery power of PTSD genome...

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Bibliographic Details
Published in:	Biological psychiatry (1969) Vol. 91; no. 7; pp. 626 - 636
Main Authors:	Maihofer, Adam X., Daskalakis, Nikolaos P., Denckla, Christy A., Ketema, Elizabeth, Morey, Rajendra A., Torres, Katy, Aiello, Allison E., Almli, Lynn M., Austin, S. Bryn, Borglum, Anders D., Babić, Dragan, Beckham, Jean C., Bisson, Jonathan I., Boks, Marco P., Bryant, Richard A., Bustamante, Angela C., Caldas-de-Almeida, José M., Chen, Chia-Yen, Dale, Anders M., Deckert, Jürgen, Delahanty, Douglas L., Domschke, Katharina, Džubur Kulenović, Alma, Erbes, Christopher R., Farrer, Lindsay A., Flory, Janine D., Forbes, David, Franz, Carol E., Gautam, Aarti, Gelaye, Bizu, Geuze, Elbert, Gillespie, Charles F., Goçi, Aferdita, Guffanti, Guia, Hauser, Michael A., Heath, Andrew C., Hemmings, Sian M.J., Hougaard, David Michael, Jett, Marti, Qin, Xue-Jun, Karstoft, Karen-Inge, Kaufman, Milissa L., Kessler, Ronald C., Koen, Nastassja, Kranzler, Henry R., Kremen, William S., Lawford, Bruce R., Liberzon, Israel, Lori, Adriana, Lugonja, Božo, Luykx, Jurjen J., Marmar, Charles, Martin, Nicholas G., Maurer, Douglas, Mavissakalian, Matig R., McFarlane, Alexander, McLean, Samuel A., Mellor, Rebecca, Michopoulos, Vasiliki, Milberg, William, Morris, Charles Phillip, Nelson, Elliot C., Nordentoft, Merete, Norman, Sonya B., O’Donnell, Meaghan, Peterson, Alan L., Pietrzak, Robert H., Roberts, Andrea L., Rothbaum, Barbara O., Rung, Ariane, Sanchez, Sixto E., Schijven, Dick, Seedat, Soraya, Seng, Julia S., Sheerin, Christina M., Silove, Derrick, Smith, Alicia K., Smoller, Jordan W., Sponheim, Scott R., Stein, Dan J., Teicher, Martin H., Thompson, Wesley K., van den Heuvel, Leigh Luella, Van Hooff, Miranda, Vinkers, Christiaan H., Wang, Yunpeng, Wang, Zhewu, Williams, Michelle A., Winternitz, Sherry, Wolf, Christiane, Wolf, Erika J., Young, Ross McD, Zhao, Hongyu, Zoellner, Lori A., Provost, Allison C., Sebat, Jonathan, Shaffer, Richard A., Koenen, Karestan C., Stein, Murray B., Nievergelt, Caroline M.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01.04.2022
Subjects:	Genetic Predisposition to Disease Genetics Genome-Wide Association Study - methods GWAS Heritability Humans Phenotype PheWAS Polymorphism, Single Nucleotide - genetics Psychiatric/Mental Health PTSD Stress Disorders, Post-Traumatic - genetics Trauma PheWAS PTSD Genetics Heritability GWAS Trauma
ISSN:	0006-3223, 1873-2402, 1873-2402
Online Access:	Get full text
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