A map of the cis-regulatory sequences in the mouse genome

A genomic map of nearly 300,000 potential cis -regulatory sequences determined from diverse mouse tissues and cell types reveals active promoters, enhancers and CCCTC-binding factor sites encompassing 11% of the mouse genome and significantly expands annotation of mammalian regulatory sequences. Fur...

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Vydáno v:	Nature (London) Ročník 488; číslo 7409; s. 116 - 120
Hlavní autoři:	Shen, Yin, Yue, Feng, McCleary, David F., Ye, Zhen, Edsall, Lee, Kuan, Samantha, Wagner, Ulrich, Dixon, Jesse, Lee, Leonard, Lobanenkov, Victor V., Ren, Bing
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	London Nature Publishing Group UK 02.08.2012 Nature Publishing Group
Témata:	631/1647/334/1874/345 631/208/199 631/208/200 631/208/212 Acetylation Animal genetics Animals Biological and medical sciences Chromatin - metabolism Chromatin Immunoprecipitation Classical genetics, quantitative genetics, hybrids Conserved Sequence DNA sequencing Enhancer Elements, Genetic - genetics Evolution, Molecular Fundamental and applied biological sciences. Psychology Gene Expression Regulation - genetics Genetics of eukaryotes. Biological and molecular evolution Genome - genetics Genomics Humanities and Social Sciences letter Male Methylation Mice - genetics Mice, Inbred C57BL Molecular Sequence Annotation multidisciplinary Nucleotide Motifs Nucleotide sequencing Organ Specificity Physical Chromosome Mapping Promoter Regions, Genetic - genetics Regulatory Sequences, Nucleic Acid - genetics Science Science (multidisciplinary) Sequence Analysis, DNA Transcription Factors - metabolism Vertebrata United States Vertebrata Mammalia Nucleotide sequence Mouse Rodentia Regulatory sequence Genome Physical map
ISSN:	0028-0836, 1476-4687, 1476-4687
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