Coverage of Blood Vessels by Astrocytic Endfeet Is Reduced in Major Depressive Disorder

Depression and cerebrovascular disease influence each other, according to clinical studies. Despite this evidence, no studies have investigated the relationship between major depressive disorder (MDD) and cerebrovascular disease at the cellular level. Astrocytic processes are a crucial interface bet...

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Bibliographic Details
Published in:	Biological psychiatry (1969) Vol. 73; no. 7; pp. 613 - 621
Main Authors:	Rajkowska, Grazyna, Hughes, Jonathan, Stockmeier, Craig A., Javier Miguel-Hidalgo, Jose, Maciag, Dorota
Format:	Journal Article
Language:	English
Published:	New York, NY Elsevier Inc 01.04.2013 Elsevier
Subjects:	Adolescent Adult Adult and adolescent clinical studies Aquaporin-4 Astrocytes - pathology Biological and medical sciences Blood Vessels - pathology blood-brain barrier Case-Control Studies cerebrovascular disease Depression Depressive Disorder, Major - pathology Female GFAP glia Humans Male Medical sciences Middle Aged Mood disorders Nerve Fibers, Myelinated - pathology Nerve Fibers, Unmyelinated - pathology Neurology neurovascular unit Prefrontal Cortex - blood supply Prefrontal Cortex - pathology Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Vascular diseases and vascular malformations of the nervous system blood-brain barrier Aquaporin-4 cerebrovascular disease glia GFAP neurovascular unit Mood disorder Nervous system diseases Neuroglia Glial fibrillary acidic protein Central nervous system Depression Astrocyte Blood brain barrier Encephalon Cerebral disorder Blood vessel Central nervous system disease Circulatory system Aquaporin Cerebrovascular disease
ISSN:	0006-3223, 1873-2402, 1873-2402
Online Access:	Get full text
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