Reprogramming of murine and human somatic cells using a single polycistronic vector

Directed reprogramming of somatic cells by defined factors provides a novel method for the generation of patient-specific stem cells with the potential to bypass both the practical and ethical concerns associated with somatic cell nuclear transfer (SCNT) and human embryonic stem (hES) cells. Althoug...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS Jg. 106; H. 1; S. 157
Hauptverfasser:	Carey, Bryce W, Markoulaki, Styliani, Hanna, Jacob, Saha, Kris, Gao, Qing, Mitalipova, Maisam, Jaenisch, Rudolf
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 06.01.2009
Schlagworte:	Animals Cells Cells, Cultured Cellular Reprogramming - genetics Fibroblasts - cytology Genetic Vectors - genetics Keratinocytes - cytology Kruppel-Like Transcription Factors - genetics Mice Octamer Transcription Factor-3 - genetics Pluripotent Stem Cells - cytology Proto-Oncogene Proteins c-myc - genetics SOXB1 Transcription Factors - genetics Transfection - methods Transgenes - genetics
ISSN:	1091-6490, 1091-6490
Online-Zugang:	Weitere Angaben
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!