New roles for the BLyS/BAFF family in antigen-experienced B cell niches

BLyS family members govern selection and survival of cells in the pre-immune B cell compartment, and emerging evidence suggests similar roles in antigen-experienced B cell pools. We review the features of this family, with particular emphasis on recent findings of how BLyS influences affinity matura...

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Veröffentlicht in:	Cytokine & growth factor reviews Jg. 25; H. 2; S. 107 - 113
Hauptverfasser:	Goenka, Radhika, Scholz, Jean L., Sindhava, Vishal J., Cancro, Michael P.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Elsevier Ltd 01.04.2014
Schlagworte:	Advanced Basic Science Antigen Presentation - immunology B-Cell Activating Factor - immunology B-Lymphocytes - immunology BAFF BLyS Cell Differentiation - immunology Cell Survival - immunology Germinal center Germinal Center - immunology Humans TACI Tumor Necrosis Factor Ligand Superfamily Member 13 - immunology BAFF BLyS TACI Germinal center
ISSN:	1359-6101, 1879-0305, 1879-0305
Online-Zugang:	Volltext
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