Development of 3D Microvascular Networks Within Gelatin Hydrogels Using Thermoresponsive Sacrificial Microfibers

A 3D microvascularized gelatin hydrogel is produced using thermoresponsive sacrificial poly(N‐isopropylacrylamide) microfibers. The capillary‐like microvascular network allows constant perfusion of media throughout the thick hydrogel, and significantly improves the viability of human neonatal dermal...

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Veröffentlicht in:	Advanced healthcare materials Jg. 5; H. 7; S. 781 - 785
Hauptverfasser:	Lee, Jung Bok, Wang, Xintong, Faley, Shannon, Baer, Bradly, Balikov, Daniel A., Sung, Hak-Joon, Bellan, Leon M.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Germany Blackwell Publishing Ltd 06.04.2016 Wiley Subscription Services, Inc
Schlagworte:	Acrylic Resins - pharmacology artificial vasculature Constants Dermis - cytology Encapsulation Fibroblasts Fibroblasts - cytology Fibroblasts - drug effects Gelatin - pharmacology gelatin hydrogel Gelatins Humans Hydrogels Hydrogels - pharmacology Imaging, Three-Dimensional Infant, Newborn Microfibers Microscopy, Confocal Microvessels - drug effects Networks Perfusion poly(N-isopropylacrylamide) Temperature Three dimensional tissue engineering poly(N-isopropylacrylamide) tissue engineering gelatin hydrogel artificial vasculature microfibers
ISSN:	2192-2640, 2192-2659, 2192-2659
Online-Zugang:	Volltext
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