MicroRNAs are minor constituents of extracellular vesicles that are rarely delivered to target cells

Mammalian cells release different types of vesicles, collectively termed extracellular vesicles (EVs). EVs contain cellular microRNAs (miRNAs) with an apparent potential to deliver their miRNA cargo to recipient cells to affect the stability of individual mRNAs and the cells’ transcriptome. The exte...

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Bibliographic Details
Published in:	PLoS genetics Vol. 17; no. 12; p. e1009951
Main Authors:	Albanese, Manuel, Chen, Yen-Fu Adam, Hüls, Corinna, Gärtner, Kathrin, Tagawa, Takanobu, Mejias-Perez, Ernesto, Keppler, Oliver T., Göbel, Christine, Zeidler, Reinhard, Shein, Mikhail, Schütz, Anne K., Hammerschmidt, Wolfgang
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 06.12.2021 Public Library of Science (PLoS)
Subjects:	Analysis Animals Biology and life sciences Cell Communication - genetics Cells Composition Extracellular Vesicles - genetics Flow Cytometry HEK293 Cells Humans Identification and classification Luciferases - genetics Medicine and Health Sciences MicroRNA MicroRNAs - genetics Plasmids - genetics Properties Research and analysis methods RNA, Messenger - genetics Transcriptome - genetics Transfection United States
ISSN:	1553-7404, 1553-7390, 1553-7404
Online Access:	Get full text
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