Evaluation of antioxidant, anti-inflammatory, anticancer activities and molecular docking of Moringa oleifera seed oil extract against experimental model of Ehrlich ascites carcinoma in Swiss female albino mice

The current research intended to evaluate the antitumor properties of Moringa oleifera oil extract (MOE). Fifty-six female Swiss albino mice were employed in this study. Animals were assigned into four groups: control (C) group, moringa oil extract (MOE) group administered (500 mg/kg b. wt) MOE dail...

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Vydané v:BMC complementary and alternative medicine Ročník 23; číslo 1; s. 457
Hlavní autori: Aldayel, Tahany Saleh, Gad El Hak, Heba N., Nafie, Mohamed S., Saad, Raneem, Abdelrazek, Heba M. A., Kilany, Omnia E.
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: London BioMed Central 14.12.2023
BioMed Central Ltd
Springer Nature B.V
BMC
Predmet:
albino
Amino acids
Analysis
Anti-inflammatory drugs
Anticancer properties
Antioxidants
Antitumor activity
Apoptosis
Ascites
Binding
Body weight
Cancer
Cancer therapies
Carcinoma
Care and treatment
Cell cycle
Cell viability
Chiropractic Medicine
Cinnamic acid
complement
Complementary & Alternative Medicine
Creatinine
Cytokines
Damage prevention
Ehrlich ascites carcinoma
Ellagic acid
Females
Gallic acid
Glucose
Hesperidin
histopathology
Inflammation
Internal Medicine
Kidney
Kidneys
Liquid chromatography
Liver
Medicine
Medicine & Public Health
Molecular docking
Moringa oleifera
Moringa olifera oil extract
Oils & fats
Oxidative stress
Pathogenesis
Proteins
Quercetin
seed oils
Seeds
Tumors
Vanillin
Weight reduction
Antioxidants
oil extract
Cytokines
Liver
Kidney
Ehrlich ascites carcinoma
Moringa olifera oil extract
ISSN:2662-7671, 2662-7671, 1472-6882
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Abstract The current research intended to evaluate the antitumor properties of Moringa oleifera oil extract (MOE). Fifty-six female Swiss albino mice were employed in this study. Animals were assigned into four groups: control (C) group, moringa oil extract (MOE) group administered (500 mg/kg b. wt) MOE daily via gavage, Ehrlich ascites carcinoma (EAC) group and EAC group administered daily with (500 mg/kg b.wt) MOE for two weeks (EAC/MOE). The results showed that MOE significantly ameliorated the EAC increase in body weight and reduced the EAC cell viability. In addition, they upgraded the levels of hepatic and renal functions, inflammatory cytokines, oxidative stress markers and EAC-induced hepatic and renal histopathological changes. Treatment of EAC with MOE induced antitumor, anti-inflammatory and antioxidant effects and normalized most of the tested parameters besides the histopathological alterations in both renal and hepatic tissues. HPLC for the MOE identified Cinnamic acid, Ellagic acid, Quercetin, Gallic acid, Vanillin and Hesperidin as major compounds. The molecular docking study highlighted the virtual binding of the identified compounds inside the GSH and SOD proteins, especially for Quercetin which exhibited promising binding affinity with good interactive binding mode with the key amino acids. These results demonstrate that the antitumor constituents of MOE against EAC induced oxidative stress and inflammation by preventing oxidative damage and controlling EAC increase.
AbstractList The current research intended to evaluate the antitumor properties of Moringa oleifera oil extract (MOE). Fifty-six female Swiss albino mice were employed in this study. Animals were assigned into four groups: control (C) group, moringa oil extract (MOE) group administered (500 mg/kg b. wt) MOE daily via gavage, Ehrlich ascites carcinoma (EAC) group and EAC group administered daily with (500 mg/kg b.wt) MOE for two weeks (EAC/MOE). The results showed that MOE significantly ameliorated the EAC increase in body weight and reduced the EAC cell viability. In addition, they upgraded the levels of hepatic and renal functions, inflammatory cytokines, oxidative stress markers and EAC-induced hepatic and renal histopathological changes. Treatment of EAC with MOE induced antitumor, anti-inflammatory and antioxidant effects and normalized most of the tested parameters besides the histopathological alterations in both renal and hepatic tissues. HPLC for the MOE identified Cinnamic acid, Ellagic acid, Quercetin, Gallic acid, Vanillin and Hesperidin as major compounds. The molecular docking study highlighted the virtual binding of the identified compounds inside the GSH and SOD proteins, especially for Quercetin which exhibited promising binding affinity with good interactive binding mode with the key amino acids. These results demonstrate that the antitumor constituents of MOE against EAC induced oxidative stress and inflammation by preventing oxidative damage and controlling EAC increase.
The current research intended to evaluate the antitumor properties of Moringa oleifera oil extract (MOE). Fifty-six female Swiss albino mice were employed in this study. Animals were assigned into four groups: control (C) group, moringa oil extract (MOE) group administered (500 mg/kg b. wt) MOE daily via gavage, Ehrlich ascites carcinoma (EAC) group and EAC group administered daily with (500 mg/kg b.wt) MOE for two weeks (EAC/MOE). The results showed that MOE significantly ameliorated the EAC increase in body weight and reduced the EAC cell viability. In addition, they upgraded the levels of hepatic and renal functions, inflammatory cytokines, oxidative stress markers and EAC-induced hepatic and renal histopathological changes. Treatment of EAC with MOE induced antitumor, anti-inflammatory and antioxidant effects and normalized most of the tested parameters besides the histopathological alterations in both renal and hepatic tissues. HPLC for the MOE identified Cinnamic acid, Ellagic acid, Quercetin, Gallic acid, Vanillin and Hesperidin as major compounds. The molecular docking study highlighted the virtual binding of the identified compounds inside the GSH and SOD proteins, especially for Quercetin which exhibited promising binding affinity with good interactive binding mode with the key amino acids. These results demonstrate that the antitumor constituents of MOE against EAC induced oxidative stress and inflammation by preventing oxidative damage and controlling EAC increase. Keywords: Antioxidants, Cytokines, Ehrlich ascites carcinoma, Liver, Kidney, Moringa olifera oil extract
The current research intended to evaluate the antitumor properties of Moringa oleifera oil extract (MOE). Fifty-six female Swiss albino mice were employed in this study. Animals were assigned into four groups: control (C) group, moringa oil extract (MOE) group administered (500 mg/kg b. wt) MOE daily via gavage, Ehrlich ascites carcinoma (EAC) group and EAC group administered daily with (500 mg/kg b.wt) MOE for two weeks (EAC/MOE). The results showed that MOE significantly ameliorated the EAC increase in body weight and reduced the EAC cell viability. In addition, they upgraded the levels of hepatic and renal functions, inflammatory cytokines, oxidative stress markers and EAC-induced hepatic and renal histopathological changes. Treatment of EAC with MOE induced antitumor, anti-inflammatory and antioxidant effects and normalized most of the tested parameters besides the histopathological alterations in both renal and hepatic tissues. HPLC for the MOE identified Cinnamic acid, Ellagic acid, Quercetin, Gallic acid, Vanillin and Hesperidin as major compounds. The molecular docking study highlighted the virtual binding of the identified compounds inside the GSH and SOD proteins, especially for Quercetin which exhibited promising binding affinity with good interactive binding mode with the key amino acids. These results demonstrate that the antitumor constituents of MOE against EAC induced oxidative stress and inflammation by preventing oxidative damage and controlling EAC increase.
The current research intended to evaluate the antitumor properties of Moringa oleifera oil extract (MOE). Fifty-six female Swiss albino mice were employed in this study. Animals were assigned into four groups: control (C) group, moringa oil extract (MOE) group administered (500 mg/kg b. wt) MOE daily via gavage, Ehrlich ascites carcinoma (EAC) group and EAC group administered daily with (500 mg/kg b.wt) MOE for two weeks (EAC/MOE). The results showed that MOE significantly ameliorated the EAC increase in body weight and reduced the EAC cell viability. In addition, they upgraded the levels of hepatic and renal functions, inflammatory cytokines, oxidative stress markers and EAC-induced hepatic and renal histopathological changes. Treatment of EAC with MOE induced antitumor, anti-inflammatory and antioxidant effects and normalized most of the tested parameters besides the histopathological alterations in both renal and hepatic tissues. HPLC for the MOE identified Cinnamic acid, Ellagic acid, Quercetin, Gallic acid, Vanillin and Hesperidin as major compounds. The molecular docking study highlighted the virtual binding of the identified compounds inside the GSH and SOD proteins, especially for Quercetin which exhibited promising binding affinity with good interactive binding mode with the key amino acids. These results demonstrate that the antitumor constituents of MOE against EAC induced oxidative stress and inflammation by preventing oxidative damage and controlling EAC increase.
The current research intended to evaluate the antitumor properties of Moringa oleifera oil extract (MOE). Fifty-six female Swiss albino mice were employed in this study. Animals were assigned into four groups: control (C) group, moringa oil extract (MOE) group administered (500 mg/kg b. wt) MOE daily via gavage, Ehrlich ascites carcinoma (EAC) group and EAC group administered daily with (500 mg/kg b.wt) MOE for two weeks (EAC/MOE). The results showed that MOE significantly ameliorated the EAC increase in body weight and reduced the EAC cell viability. In addition, they upgraded the levels of hepatic and renal functions, inflammatory cytokines, oxidative stress markers and EAC-induced hepatic and renal histopathological changes. Treatment of EAC with MOE induced antitumor, anti-inflammatory and antioxidant effects and normalized most of the tested parameters besides the histopathological alterations in both renal and hepatic tissues. HPLC for the MOE identified Cinnamic acid, Ellagic acid, Quercetin, Gallic acid, Vanillin and Hesperidin as major compounds. The molecular docking study highlighted the virtual binding of the identified compounds inside the GSH and SOD proteins, especially for Quercetin which exhibited promising binding affinity with good interactive binding mode with the key amino acids. These results demonstrate that the antitumor constituents of MOE against EAC induced oxidative stress and inflammation by preventing oxidative damage and controlling EAC increase.The current research intended to evaluate the antitumor properties of Moringa oleifera oil extract (MOE). Fifty-six female Swiss albino mice were employed in this study. Animals were assigned into four groups: control (C) group, moringa oil extract (MOE) group administered (500 mg/kg b. wt) MOE daily via gavage, Ehrlich ascites carcinoma (EAC) group and EAC group administered daily with (500 mg/kg b.wt) MOE for two weeks (EAC/MOE). The results showed that MOE significantly ameliorated the EAC increase in body weight and reduced the EAC cell viability. In addition, they upgraded the levels of hepatic and renal functions, inflammatory cytokines, oxidative stress markers and EAC-induced hepatic and renal histopathological changes. Treatment of EAC with MOE induced antitumor, anti-inflammatory and antioxidant effects and normalized most of the tested parameters besides the histopathological alterations in both renal and hepatic tissues. HPLC for the MOE identified Cinnamic acid, Ellagic acid, Quercetin, Gallic acid, Vanillin and Hesperidin as major compounds. The molecular docking study highlighted the virtual binding of the identified compounds inside the GSH and SOD proteins, especially for Quercetin which exhibited promising binding affinity with good interactive binding mode with the key amino acids. These results demonstrate that the antitumor constituents of MOE against EAC induced oxidative stress and inflammation by preventing oxidative damage and controlling EAC increase.
Abstract The current research intended to evaluate the antitumor properties of Moringa oleifera oil extract (MOE). Fifty-six female Swiss albino mice were employed in this study. Animals were assigned into four groups: control (C) group, moringa oil extract (MOE) group administered (500 mg/kg b. wt) MOE daily via gavage, Ehrlich ascites carcinoma (EAC) group and EAC group administered daily with (500 mg/kg b.wt) MOE for two weeks (EAC/MOE). The results showed that MOE significantly ameliorated the EAC increase in body weight and reduced the EAC cell viability. In addition, they upgraded the levels of hepatic and renal functions, inflammatory cytokines, oxidative stress markers and EAC-induced hepatic and renal histopathological changes. Treatment of EAC with MOE induced antitumor, anti-inflammatory and antioxidant effects and normalized most of the tested parameters besides the histopathological alterations in both renal and hepatic tissues. HPLC for the MOE identified Cinnamic acid, Ellagic acid, Quercetin, Gallic acid, Vanillin and Hesperidin as major compounds. The molecular docking study highlighted the virtual binding of the identified compounds inside the GSH and SOD proteins, especially for Quercetin which exhibited promising binding affinity with good interactive binding mode with the key amino acids. These results demonstrate that the antitumor constituents of MOE against EAC induced oxidative stress and inflammation by preventing oxidative damage and controlling EAC increase.
ArticleNumber 457
Audience Academic
Author Saad, Raneem
Gad El Hak, Heba N.
Aldayel, Tahany Saleh
Kilany, Omnia E.
Abdelrazek, Heba M. A.
Nafie, Mohamed S.
Author_xml – sequence: 1
  givenname: Tahany Saleh
  surname: Aldayel
  fullname: Aldayel, Tahany Saleh
  organization: Department of Health Sciences, Clinical Nutrition, College of Health and Rehabilitation Sciences, Princess Nourah bint Abdulrahman University
– sequence: 2
  givenname: Heba N.
  surname: Gad El Hak
  fullname: Gad El Hak, Heba N.
  email: heba_ahmed@science.suez.edu.eg
  organization: Department of Zoology, Faculty of Science, Suez Canal University
– sequence: 3
  givenname: Mohamed S.
  surname: Nafie
  fullname: Nafie, Mohamed S.
  organization: Chemistry Department, Faculty of Science, Suez Canal University
– sequence: 4
  givenname: Raneem
  surname: Saad
  fullname: Saad, Raneem
  organization: Department of Clinical Pathology, Faculty of Veterinary Medicine, Suez Canal University
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  givenname: Heba M. A.
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  givenname: Omnia E.
  surname: Kilany
  fullname: Kilany, Omnia E.
  organization: Department of Clinical Pathology, Faculty of Veterinary Medicine, Suez Canal University
BackLink https://www.ncbi.nlm.nih.gov/pubmed/38098043$$D View this record in MEDLINE/PubMed
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CitedBy_id crossref_primary_10_1007_s40495_024_00383_x
crossref_primary_10_1051_bioconf_202518301008
crossref_primary_10_3390_ph18091410
Cites_doi 10.1016/j.biopha.2005.03.005
10.1007/s13596-011-0001-y
10.1088/1755-1315/807/2/022008
10.1016/j.ccm.2017.11.005
10.1108/NFS-03-2020-0087
10.21608/jbaar.2016.106941
10.1038/ncomms2750
10.1038/nri1703
10.1155/2009/405016
10.7314/APJCP.2014.15.20.8571
10.2174/1871520619666181224121004
10.1002/ajpa.21031
10.1177/1010428317695923
10.1110/ps.052055206
10.3109/02699052.2015.1065344
10.1080/07315724.2020.1735572
10.1177/0885066607299510
10.1111/jfbc.13579
10.1038/s41598-021-96509-y
10.2174/187152711794480429
10.1186/s12943-019-0983-5
10.1016/j.lfs.2005.10.006
10.1371/journal.pone.0046858
10.1016/j.fct.2014.06.027
10.1038/s41598-016-0028-x
10.7314/APJCP.2012.13.12.6295
10.1016/j.biopha.2018.09.060
10.1002/ptr.5271
10.4081/jphia.2018.841
10.1016/S1359-6101(02)00027-8
10.3748/wjg.v20.i9.2279
10.1007/s11356-020-09643-x
10.2334/josnusd.56.135
10.1002/jcc.21334
10.5507/bp.2010.017
10.3390/biomedicines9080932
10.3390/nu14051025
10.1007/s11356-021-13904-8
10.1515/CCLM.2000.201
10.1038/nrclinonc.2018.8
10.1038/nrc1717
10.1016/j.etp.2011.08.009
10.1016/j.ijbiomac.2017.10.070
10.1002/bies.20027
10.1186/1471-2407-13-600
10.1371/journal.pone.0135814
10.1016/j.jep.2007.12.010
10.1016/j.indcrop.2012.09.021
10.2174/1871520620666200728131219
10.3109/07420529909019085
10.5897/JPP2019.0551
10.1002/mdc3.13129
10.1016/1043-2760(94)00144-S
10.21608/edj.2018.77385
10.1016/j.ahj.2009.07.024
10.1016/S0006-3223(97)00206-0
10.1155/2015/948737
10.1016/S1383-5718(99)00025-X
10.1007/s11356-019-06528-6
10.1038/nrd2110
10.2174/1573402111666150529130922
10.1016/j.cca.2007.12.025
10.1007/s13277-013-1447-y
10.1016/j.sjbs.2021.02.056
10.1038/s41598-019-56847-4
10.1002/cncr.33587
10.1016/j.adcanc.2022.100029
10.1016/j.ijbiomac.2019.03.210
10.1016/j.steroids.2019.108485
10.1016/j.phrs.2015.09.001
10.1016/S0753-3322(03)00043-X
10.1016/S0304-3835(99)00366-3
10.1002/tox.22888
10.1016/j.nano.2011.05.008
10.1016/j.jep.2010.03.010
10.1016/j.jep.2003.09.024
10.1016/j.biopha.2017.05.043
10.3390/cancers11111704
10.1002/pbc.27660
10.5897/JMPR2013.5353
10.1038/s41598-021-86721-1
10.4049/jimmunol.157.1.160
10.1016/j.fct.2011.03.006
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Issue 1
Keywords Antioxidants
oil extract
Cytokines
Liver
Kidney
Ehrlich ascites carcinoma
Moringa olifera oil extract
Language English
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References 4279_CR28
M Nadro (4279_CR79) 2006; 5
R Téllez-Sanz (4279_CR102) 2006; 15
R Venkataraman (4279_CR67) 2007; 22
DM Townsend (4279_CR77) 2003; 57
Y Zhao (4279_CR3) 2013; 2013
WS Alqahtani (4279_CR55) 2021; 45
AL Miranda-Vilela (4279_CR95) 2014; 35
RA Patel (4279_CR45) 2021; 8
AA Al-Ghanayem (4279_CR22) 2022; 15
D Medhat (4279_CR73) 2017; 91
JM Salsman (4279_CR35) 2019; 66
K Ishihara (4279_CR82) 2002; 13
4279_CR21
C Locatelli (4279_CR37) 2013; 1
I Matic (4279_CR17) 2018; 9
VE Steele (4279_CR7) 2010; 2010
4279_CR19
4279_CR13
SJ Campbell (4279_CR92) 2018; 39
A Gupta (4279_CR94) 2010; 48
HS Mahmoud (4279_CR83) 2021; 11
A Latifi (4279_CR11) 2012; 7
4279_CR91
S Mishra (4279_CR69) 2014; 72
WAS Brito (4279_CR10) 2021; 9
4279_CR99
KK Upadhyay (4279_CR44) 2012; 8
J Zapf (4279_CR65) 1995; 6
TF Mutar (4279_CR66) 2020; 35
AK Al-Asmari (4279_CR29) 2015; 10
S Sreelatha (4279_CR25) 2011; 49
B Bhattacharya (4279_CR98) 2011; 4
A Asaduzzaman (4279_CR41) 2018; 107
J Swierczynski (4279_CR59) 2014; 20
FZ Mohammed (4279_CR64) 2020; 20
P Jancova (4279_CR87) 2010; 154
N Kumar (4279_CR97) 2020; 10
T Ghosh (4279_CR75) 2011; 11
C Cui (4279_CR85) 2019; 132
E Tousson (4279_CR63) 2020; 27
A Roy (4279_CR36) 2018; 2
IT Abdel-Raheem (4279_CR70) 2010; 23
D Barhoi (4279_CR40) 2021; 40
S Charoensin (4279_CR27) 2014; 8
PL Walker (4279_CR42) 2009; 139
N Vincent (4279_CR90) 1967; 27
M Peet (4279_CR48) 1998; 43
B Peltanova (4279_CR5) 2019; 18
M El-Missiry (4279_CR12) 2000; 151
J Lokau (4279_CR80) 2019; 11
MD Evans (4279_CR4) 2004; 26
H Younus (4279_CR88) 2018; 12
NP Santos (4279_CR56) 2017; 39
OM Badr (4279_CR68) 2016; 2
S Gupta (4279_CR78) 2004; 90
L Beiqing (4279_CR84) 1996; 157
C Tiloke (4279_CR33) 2018; 108
F Imam (4279_CR96) 2015; 102
I Dhamija (4279_CR43) 2013; 65
4279_CR76
SJ Somani (4279_CR61) 2015; 29
HV Ratajczak (4279_CR93) 1999; 16
RT El-sharkawy (4279_CR16) 2018; 64
R Metgud (4279_CR74) 2014; 56
MB Çimen (4279_CR49) 2008; 390
RM Hoffman (4279_CR8) 2005; 5
P Chumark (4279_CR20) 2008; 116
DE Johnson (4279_CR86) 2018; 15
DG Stein (4279_CR2) 2015; 29
Z Förhécz (4279_CR47) 2009; 158
SJ Adouko (4279_CR18) 2020; 12
MS Nafie (4279_CR101) 2019; 152
4279_CR62
B Vongsak (4279_CR34) 2013; 44
L Zhou (4279_CR52) 2017; 7
FR Nascimento (4279_CR39) 2006; 78
JM McCord (4279_CR89) 2005; 59
NG Sannappa Gowda (4279_CR81) 2022; 4
M Gupta (4279_CR38) 2004; 25
HN Gad El-Hak (4279_CR57) 2022; 14
T El-Masry (4279_CR58) 2020; 33
NE Sharpless (4279_CR9) 2006; 5
M Karin (4279_CR6) 2005; 5
MA Abd Eldaim (4279_CR54) 2021; 28
S Gezici (4279_CR15) 2019; 19
F Bray (4279_CR1) 2021; 127
V Balamurugan (4279_CR31) 2014; 9
S Budda (4279_CR26) 2011; 12
T Afsar (4279_CR71) 2021; 11
4279_CR46
N Chhikara (4279_CR32) 2020; 51
N Sinha (4279_CR51) 2015; 11
RK Gupta (4279_CR60) 2012; 13
AA Fahmi (4279_CR53) 2021; 28
4279_CR104
4279_CR103
4279_CR100
AP Guevara (4279_CR23) 1999; 440
AF Abdull Razis (4279_CR24) 2014; 15
MM Abdel-Daim (4279_CR72) 2020; 27
A Bala (4279_CR50) 2010; 129
I Al-Sharif (4279_CR30) 2013; 13
M Divino da Rocha (4279_CR14) 2011; 10
References_xml – volume: 59
  start-page: 139
  issue: 4
  year: 2005
  ident: 4279_CR89
  publication-title: Biomed Pharmacother
  doi: 10.1016/j.biopha.2005.03.005
– volume: 5
  start-page: 539
  issue: 1
  year: 2006
  ident: 4279_CR79
  publication-title: Trop J Pharm Res
– volume: 11
  start-page: 41
  issue: 1
  year: 2011
  ident: 4279_CR75
  publication-title: Orient Pharm Experimental Med
  doi: 10.1007/s13596-011-0001-y
– ident: 4279_CR19
– ident: 4279_CR21
  doi: 10.1088/1755-1315/807/2/022008
– volume: 39
  start-page: 79
  issue: 1
  year: 2018
  ident: 4279_CR92
  publication-title: Clin Chest Med
  doi: 10.1016/j.ccm.2017.11.005
– volume: 2010
  start-page: 327
  year: 2010
  ident: 4279_CR7
  publication-title: Elsevier
– volume: 51
  start-page: 255
  issue: 2
  year: 2020
  ident: 4279_CR32
  publication-title: Nutr Food Sci
  doi: 10.1108/NFS-03-2020-0087
– volume: 2
  start-page: 185
  issue: 3
  year: 2016
  ident: 4279_CR68
  publication-title: J Bioscience Appl Res
  doi: 10.21608/jbaar.2016.106941
– ident: 4279_CR100
– ident: 4279_CR103
  doi: 10.1038/ncomms2750
– volume: 5
  start-page: 749
  issue: 10
  year: 2005
  ident: 4279_CR6
  publication-title: Nat Rev Immunol
  doi: 10.1038/nri1703
– ident: 4279_CR46
  doi: 10.1155/2009/405016
– volume: 15
  start-page: 8571
  issue: 20
  year: 2014
  ident: 4279_CR24
  publication-title: Asian Pac J Cancer Prev
  doi: 10.7314/APJCP.2014.15.20.8571
– volume: 19
  start-page: 101
  issue: 1
  year: 2019
  ident: 4279_CR15
  publication-title: Anticancer Agents Med Chem
  doi: 10.2174/1871520619666181224121004
– volume: 139
  start-page: 109
  issue: 2
  year: 2009
  ident: 4279_CR42
  publication-title: Am J Phys Anthropol
  doi: 10.1002/ajpa.21031
– volume: 39
  start-page: 101042831769592
  issue: 3
  year: 2017
  ident: 4279_CR56
  publication-title: Tumor Biology
  doi: 10.1177/1010428317695923
– volume: 15
  start-page: 1093
  issue: 5
  year: 2006
  ident: 4279_CR102
  publication-title: Protein Sci
  doi: 10.1110/ps.052055206
– volume: 29
  start-page: 1259
  issue: 11
  year: 2015
  ident: 4279_CR2
  publication-title: Brain Inj
  doi: 10.3109/02699052.2015.1065344
– volume: 40
  start-page: 70
  issue: 1
  year: 2021
  ident: 4279_CR40
  publication-title: J Am Coll Nutr
  doi: 10.1080/07315724.2020.1735572
– volume: 22
  start-page: 187
  issue: 4
  year: 2007
  ident: 4279_CR67
  publication-title: J Intensive Care Med
  doi: 10.1177/0885066607299510
– volume: 23
  start-page: 21
  issue: 1
  year: 2010
  ident: 4279_CR70
  publication-title: Pak J Pharm Sci
– volume: 45
  start-page: e13579
  issue: 1
  year: 2021
  ident: 4279_CR55
  publication-title: J Food Biochem
  doi: 10.1111/jfbc.13579
– volume: 11
  start-page: 1
  issue: 1
  year: 2021
  ident: 4279_CR71
  publication-title: Sci Rep
  doi: 10.1038/s41598-021-96509-y
– volume: 4
  start-page: 567
  issue: 3
  year: 2011
  ident: 4279_CR98
  publication-title: J Pharm Res
– volume: 10
  start-page: 251
  issue: 2
  year: 2011
  ident: 4279_CR14
  publication-title: CNS Neurol Disord Drug Targets
  doi: 10.2174/187152711794480429
– volume: 18
  start-page: 1
  issue: 1
  year: 2019
  ident: 4279_CR5
  publication-title: Mol Cancer
  doi: 10.1186/s12943-019-0983-5
– volume: 78
  start-page: 2650
  issue: 22
  year: 2006
  ident: 4279_CR39
  publication-title: Life Sci
  doi: 10.1016/j.lfs.2005.10.006
– volume: 7
  start-page: e46858
  issue: 10
  year: 2012
  ident: 4279_CR11
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0046858
– volume: 72
  start-page: 20
  year: 2014
  ident: 4279_CR69
  publication-title: Food Chem Toxicol
  doi: 10.1016/j.fct.2014.06.027
– volume: 7
  start-page: 1
  issue: 1
  year: 2017
  ident: 4279_CR52
  publication-title: Sci Rep
  doi: 10.1038/s41598-016-0028-x
– volume: 13
  start-page: 6295
  issue: 12
  year: 2012
  ident: 4279_CR60
  publication-title: Asian Pac J Cancer Prev
  doi: 10.7314/APJCP.2012.13.12.6295
– volume: 108
  start-page: 457
  year: 2018
  ident: 4279_CR33
  publication-title: Biomed Pharmacother
  doi: 10.1016/j.biopha.2018.09.060
– volume: 29
  start-page: 339
  issue: 3
  year: 2015
  ident: 4279_CR61
  publication-title: Phytother Res
  doi: 10.1002/ptr.5271
– volume: 9
  start-page: 841
  issue: 3
  year: 2018
  ident: 4279_CR17
  publication-title: J Public Health Afr
  doi: 10.4081/jphia.2018.841
– volume: 13
  start-page: 357
  issue: 4–5
  year: 2002
  ident: 4279_CR82
  publication-title: Cytokine Growth Factor Rev
  doi: 10.1016/S1359-6101(02)00027-8
– volume: 20
  start-page: 2279
  issue: 9
  year: 2014
  ident: 4279_CR59
  publication-title: World J Gastroenterology
  doi: 10.3748/wjg.v20.i9.2279
– volume: 27
  start-page: 33723
  issue: 27
  year: 2020
  ident: 4279_CR72
  publication-title: Environ Sci Pollut Res
  doi: 10.1007/s11356-020-09643-x
– volume: 12
  start-page: 88
  issue: 3
  year: 2018
  ident: 4279_CR88
  publication-title: Int J Health Sci
– volume: 56
  start-page: 135
  issue: 2
  year: 2014
  ident: 4279_CR74
  publication-title: J Oral Sci
  doi: 10.2334/josnusd.56.135
– ident: 4279_CR104
  doi: 10.1002/jcc.21334
– ident: 4279_CR13
– volume: 15
  issue: 5
  year: 2022
  ident: 4279_CR22
  publication-title: Pharmaceuticals
– volume: 154
  start-page: 103
  issue: 2
  year: 2010
  ident: 4279_CR87
  publication-title: Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub
  doi: 10.5507/bp.2010.017
– volume: 9
  start-page: 932
  issue: 8
  year: 2021
  ident: 4279_CR10
  publication-title: Biomedicines
  doi: 10.3390/biomedicines9080932
– volume: 14
  start-page: 1025
  issue: 5
  year: 2022
  ident: 4279_CR57
  publication-title: Nutrients
  doi: 10.3390/nu14051025
– volume: 28
  start-page: 44226
  issue: 32
  year: 2021
  ident: 4279_CR54
  publication-title: Environ Sci Pollut Res
  doi: 10.1007/s11356-021-13904-8
– ident: 4279_CR76
  doi: 10.1515/CCLM.2000.201
– volume: 15
  start-page: 234
  issue: 4
  year: 2018
  ident: 4279_CR86
  publication-title: Nat Reviews Clin Oncol
  doi: 10.1038/nrclinonc.2018.8
– volume: 2
  start-page: 109
  year: 2018
  ident: 4279_CR36
  publication-title: Anticancer Plants
– volume: 5
  start-page: 796
  issue: 10
  year: 2005
  ident: 4279_CR8
  publication-title: Nat Rev Cancer
  doi: 10.1038/nrc1717
– volume: 65
  start-page: 235
  issue: 3
  year: 2013
  ident: 4279_CR43
  publication-title: Exp Toxicol Pathol
  doi: 10.1016/j.etp.2011.08.009
– volume: 107
  start-page: 1936
  year: 2018
  ident: 4279_CR41
  publication-title: Int J Biol Macromol
  doi: 10.1016/j.ijbiomac.2017.10.070
– ident: 4279_CR99
– volume: 26
  start-page: 533
  issue: 5
  year: 2004
  ident: 4279_CR4
  publication-title: BioEssays
  doi: 10.1002/bies.20027
– volume: 13
  start-page: 600
  year: 2013
  ident: 4279_CR30
  publication-title: BMC Cancer
  doi: 10.1186/1471-2407-13-600
– volume: 10
  start-page: e0135814
  issue: 8
  year: 2015
  ident: 4279_CR29
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0135814
– volume: 116
  start-page: 439
  issue: 3
  year: 2008
  ident: 4279_CR20
  publication-title: J Ethnopharmacol
  doi: 10.1016/j.jep.2007.12.010
– volume: 44
  start-page: 566
  year: 2013
  ident: 4279_CR34
  publication-title: Ind Crops Prod
  doi: 10.1016/j.indcrop.2012.09.021
– volume: 20
  start-page: 2246
  issue: 18
  year: 2020
  ident: 4279_CR64
  publication-title: Anticancer Agents Med Chem
  doi: 10.2174/1871520620666200728131219
– volume: 16
  start-page: 185
  issue: 2
  year: 1999
  ident: 4279_CR93
  publication-title: Chronobiol Int
  doi: 10.3109/07420529909019085
– volume: 12
  start-page: 1
  issue: 1
  year: 2020
  ident: 4279_CR18
  publication-title: J Pharmacognosy Phytother
  doi: 10.5897/JPP2019.0551
– volume: 8
  start-page: 193
  issue: 2
  year: 2021
  ident: 4279_CR45
  publication-title: Mov Disorders Clin Pract
  doi: 10.1002/mdc3.13129
– volume: 12
  start-page: 3221
  issue: 12
  year: 2011
  ident: 4279_CR26
  publication-title: Asian Pac J Cancer Prev
– volume: 6
  start-page: 37
  issue: 2
  year: 1995
  ident: 4279_CR65
  publication-title: Trends Endocrinol Metab
  doi: 10.1016/1043-2760(94)00144-S
– volume: 64
  start-page: 1293
  year: 2018
  ident: 4279_CR16
  publication-title: Egypt Dent J
  doi: 10.21608/edj.2018.77385
– volume: 158
  start-page: 659
  issue: 4
  year: 2009
  ident: 4279_CR47
  publication-title: Am Heart J
  doi: 10.1016/j.ahj.2009.07.024
– volume: 43
  start-page: 315
  issue: 5
  year: 1998
  ident: 4279_CR48
  publication-title: Biol Psychiatry
  doi: 10.1016/S0006-3223(97)00206-0
– ident: 4279_CR91
  doi: 10.1155/2015/948737
– volume: 440
  start-page: 181
  issue: 2
  year: 1999
  ident: 4279_CR23
  publication-title: Mutat Res
  doi: 10.1016/S1383-5718(99)00025-X
– volume: 27
  start-page: 9236
  issue: 9
  year: 2020
  ident: 4279_CR63
  publication-title: Environ Sci Pollut Res
  doi: 10.1007/s11356-019-06528-6
– volume: 25
  start-page: 1070
  year: 2004
  ident: 4279_CR38
  publication-title: Acta Pharmacol Sin
– volume: 2013
  start-page: 316523
  year: 2013
  ident: 4279_CR3
  publication-title: Oxid Med Cell Longev
– volume: 5
  start-page: 741
  issue: 9
  year: 2006
  ident: 4279_CR9
  publication-title: Nat Rev Drug Discovery
  doi: 10.1038/nrd2110
– volume: 11
  start-page: 132
  issue: 2
  year: 2015
  ident: 4279_CR51
  publication-title: Curr Hypertens Rev
  doi: 10.2174/1573402111666150529130922
– volume: 390
  start-page: 1
  issue: 1–2
  year: 2008
  ident: 4279_CR49
  publication-title: Clin Chim Acta
  doi: 10.1016/j.cca.2007.12.025
– volume: 48
  start-page: 1157
  issue: 11
  year: 2010
  ident: 4279_CR94
  publication-title: Indian J Exp Biol
– ident: 4279_CR62
– volume: 35
  start-page: 3391
  issue: 4
  year: 2014
  ident: 4279_CR95
  publication-title: Tumor Biology
  doi: 10.1007/s13277-013-1447-y
– volume: 9
  start-page: 604
  issue: 4
  year: 2014
  ident: 4279_CR31
  publication-title: ||| Bangladesh Journal of Pharmacology
– volume: 1
  start-page: 23
  year: 2013
  ident: 4279_CR37
  publication-title: Nova Publishers
– volume: 28
  start-page: 3117
  issue: 5
  year: 2021
  ident: 4279_CR53
  publication-title: Saudi J Biol Sci
  doi: 10.1016/j.sjbs.2021.02.056
– volume: 10
  start-page: 1
  issue: 1
  year: 2020
  ident: 4279_CR97
  publication-title: Sci Rep
  doi: 10.1038/s41598-019-56847-4
– volume: 127
  start-page: 3029
  issue: 16
  year: 2021
  ident: 4279_CR1
  publication-title: Cancer
  doi: 10.1002/cncr.33587
– volume: 4
  start-page: 100029
  year: 2022
  ident: 4279_CR81
  publication-title: Adv Cancer Biology - Metastasis
  doi: 10.1016/j.adcanc.2022.100029
– volume: 132
  start-page: 844
  year: 2019
  ident: 4279_CR85
  publication-title: Int J Biol Macromol
  doi: 10.1016/j.ijbiomac.2019.03.210
– volume: 152
  year: 2019
  ident: 4279_CR101
  publication-title: Steroids
  doi: 10.1016/j.steroids.2019.108485
– volume: 102
  start-page: 1
  year: 2015
  ident: 4279_CR96
  publication-title: Pharmacol Res
  doi: 10.1016/j.phrs.2015.09.001
– volume: 57
  start-page: 145
  issue: 3–4
  year: 2003
  ident: 4279_CR77
  publication-title: Biomed Pharmacother
  doi: 10.1016/S0753-3322(03)00043-X
– volume: 151
  start-page: 119
  issue: 2
  year: 2000
  ident: 4279_CR12
  publication-title: Cancer Lett
  doi: 10.1016/S0304-3835(99)00366-3
– ident: 4279_CR28
– volume: 35
  start-page: 528
  issue: 4
  year: 2020
  ident: 4279_CR66
  publication-title: Environ Toxicol
  doi: 10.1002/tox.22888
– volume: 8
  start-page: 71
  issue: 1
  year: 2012
  ident: 4279_CR44
  publication-title: Nanomed Nanotechnol Biol Med
  doi: 10.1016/j.nano.2011.05.008
– volume: 129
  start-page: 131
  issue: 1
  year: 2010
  ident: 4279_CR50
  publication-title: J Ethnopharmacol
  doi: 10.1016/j.jep.2010.03.010
– volume: 90
  start-page: 185
  issue: 2–3
  year: 2004
  ident: 4279_CR78
  publication-title: J Ethnopharmacol
  doi: 10.1016/j.jep.2003.09.024
– volume: 27
  start-page: 1058
  issue: 6Part1
  year: 1967
  ident: 4279_CR90
  publication-title: Cancer Res
– volume: 91
  start-page: 1006
  year: 2017
  ident: 4279_CR73
  publication-title: Biomed Pharmacother
  doi: 10.1016/j.biopha.2017.05.043
– volume: 11
  start-page: 1704
  issue: 11
  year: 2019
  ident: 4279_CR80
  publication-title: Cancers
  doi: 10.3390/cancers11111704
– volume: 66
  start-page: e27660
  issue: 7
  year: 2019
  ident: 4279_CR35
  publication-title: Pediatr Blood Cancer
  doi: 10.1002/pbc.27660
– volume: 8
  start-page: 318
  issue: 7
  year: 2014
  ident: 4279_CR27
  publication-title: J Med Plants Res
  doi: 10.5897/JMPR2013.5353
– volume: 11
  start-page: 7542
  issue: 1
  year: 2021
  ident: 4279_CR83
  publication-title: Sci Rep
  doi: 10.1038/s41598-021-86721-1
– volume: 157
  start-page: 160
  issue: 1
  year: 1996
  ident: 4279_CR84
  publication-title: J Immunol
  doi: 10.4049/jimmunol.157.1.160
– volume: 33
  start-page: 393
  issue: 1Supplementary
  year: 2020
  ident: 4279_CR58
  publication-title: Pak J Pharm Sci
– volume: 49
  start-page: 1270
  issue: 6
  year: 2011
  ident: 4279_CR25
  publication-title: Food Chem Toxicol
  doi: 10.1016/j.fct.2011.03.006
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Snippet The current research intended to evaluate the antitumor properties of Moringa oleifera oil extract (MOE). Fifty-six female Swiss albino mice were employed in...
The current research intended to evaluate the antitumor properties of Moringa oleifera oil extract (MOE). Fifty-six female Swiss albino mice were employed in...
Abstract The current research intended to evaluate the antitumor properties of Moringa oleifera oil extract (MOE). Fifty-six female Swiss albino mice were...
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SubjectTerms albino
Amino acids
Analysis
Anti-inflammatory drugs
Anticancer properties
Antioxidants
Antitumor activity
Apoptosis
Ascites
Binding
Body weight
Cancer
Cancer therapies
Carcinoma
Care and treatment
Cell cycle
Cell viability
Chiropractic Medicine
Cinnamic acid
complement
Complementary & Alternative Medicine
Creatinine
Cytokines
Damage prevention
Ehrlich ascites carcinoma
Ellagic acid
Females
Gallic acid
Glucose
Hesperidin
histopathology
Inflammation
Internal Medicine
Kidney
Kidneys
Liquid chromatography
Liver
Medicine
Medicine & Public Health
Molecular docking
Moringa oleifera
Moringa olifera oil extract
Oils & fats
Oxidative stress
Pathogenesis
Proteins
Quercetin
seed oils
Seeds
Tumors
Vanillin
Weight reduction
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Title Evaluation of antioxidant, anti-inflammatory, anticancer activities and molecular docking of Moringa oleifera seed oil extract against experimental model of Ehrlich ascites carcinoma in Swiss female albino mice
URI https://link.springer.com/article/10.1186/s12906-023-04279-z
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