The biological and clinical significance of emerging SARS-CoV-2 variants

The past several months have witnessed the emergence of SARS-CoV-2 variants with novel spike protein mutations that are influencing the epidemiological and clinical aspects of the COVID-19 pandemic. These variants can increase rates of virus transmission and/or increase the risk of reinfection and r...

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Bibliographic Details
Published in:	Nature reviews. Genetics Vol. 22; no. 12; pp. 757 - 773
Main Authors:	Tao, Kaiming, Tzou, Philip L, Nouhin, Janin, Gupta, Ravindra K, de Oliveira, Tulio, Kosakovsky Pond, Sergei L, Fera, Daniela, Shafer, Robert W
Format:	Journal Article
Language:	English
Published:	England Nature Publishing Group 01.12.2021
Subjects:	Biological Evolution Clinical aspects Clinical significance Coronaviruses COVID-19 COVID-19 - epidemiology COVID-19 - virology Disease transmission Epidemiology Epitopes - immunology Genetic diversity Herd immunity Humans Medical research Monoclonal antibodies Mutation Pandemics SARS-CoV-2 - pathogenicity SARS-CoV-2 - physiology Severe acute respiratory syndrome coronavirus 2 Spike Glycoprotein, Coronavirus - chemistry Spike Glycoprotein, Coronavirus - immunology Spike protein Vaccination Vaccine efficacy Viruses
ISSN:	1471-0056, 1471-0064, 1471-0064
Online Access:	Get full text
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