Construction of in vitro 3-D model for lung cancer-cell metastasis study

Background Cancer metastasis is the main cause of mortality in cancer patients. However, the drugs targeting metastasis processes are still lacking, which is partially due to the short of effective in vitro model for cell invasion studies. The traditional 2-D culture method cannot reveal the interac...

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Bibliographic Details
Published in:	BMC cancer Vol. 22; no. 1; pp. 438 - 9
Main Authors:	Jiang, Rongrong, Huang, Jiechun, Sun, Xiaotian, Chu, Xianglin, Wang, Fangrui, Zhou, Jie, Fan, Qihui, Pang, Liewen
Format:	Journal Article
Language:	English
Published:	London BioMed Central 21.04.2022 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	3-D model Alveoli Animal models Animals Biomedical and Life Sciences Biomedicine Cancer Cancer metastasis Cancer Research Care and treatment Cell adhesion & migration Cell culture Cell morphology Cell proliferation Collagen Collagen - metabolism Collagen hydrogel Complications and side effects Cytology Diagnosis Drug delivery Drug screening Epithelial cells Etching Extracellular matrix Extracellular Matrix - metabolism Health Promotion and Disease Prevention Humans Hydrogels Hydrogels - analysis Hydrogels - chemistry Hydrogels - metabolism Immunosuppressive agents Lung cancer Lung Neoplasms - metabolism Medicine/Public Health Mesenchyme Metastases Metastasis Microfluidic system Microfluidics Mimicry Morphology Neoplasm Invasiveness Oncology Oncology, Experimental Penicillin Porous materials Silicon wafers Surgical Oncology Tumor cells Tumor Microenvironment China Cancer metastasis Collagen hydrogel Drug screening Microfluidic system 3-D model
ISSN:	1471-2407, 1471-2407
Online Access:	Get full text
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