The EMIF-AD Multimodal Biomarker Discovery study: design, methods and cohort characteristics

Background There is an urgent need for novel, noninvasive biomarkers to diagnose Alzheimer’s disease (AD) in the predementia stages and to predict the rate of decline. Therefore, we set up the European Medical Information Framework for Alzheimer’s Disease Multimodal Biomarker Discovery (EMIF-AD MBD)...

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Published in:	Alzheimer's research & therapy Vol. 10; no. 1; pp. 64 - 9
Main Authors:	Bos, Isabelle, Vos, Stephanie, Vandenberghe, Rik, Scheltens, Philip, Engelborghs, Sebastiaan, Frisoni, Giovanni, Molinuevo, José Luis, Wallin, Anders, Lleó, Alberto, Popp, Julius, Martinez-Lage, Pablo, Baird, Alison, Dobson, Richard, Legido-Quigley, Cristina, Sleegers, Kristel, Van Broeckhoven, Christine, Bertram, Lars, ten Kate, Mara, Barkhof, Frederik, Zetterberg, Henrik, Lovestone, Simon, Streffer, Johannes, Visser, Pieter Jelle
Format:	Journal Article
Language:	English
Published:	London BioMed Central 06.07.2018 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	1984 1992 Aged Aged, 80 and over Alzheimer Disease - blood Alzheimer Disease - diagnosis Alzheimer's disease alzheimers-disease Amyloid beta-Peptides - blood atrophy Biological markers Biomarkers Biomarkers - blood Biomedical and Life Sciences Biomedical Research - methods Biomedicine blood-based Care and treatment Cerebrospinal fluid cerebrospinal-fluid biomarkers Chitinase-3-Like Protein 1 - blood Cognitive ability Cognitive Dysfunction Cohort Studies csf biomarkers Dementia Deoxyribonucleic acid Diagnosis DNA DNA methylation Female Genetic testing Genomics Geriatric Psychiatry Geriatrics/Gerontology Health aspects heltens p Humans Initiatives journal of neurology neurosurgery and psychiatry khann g Knowledge management Magnetic Resonance Imaging Male Medical imaging Metabolomics Middle Aged mild cognitive impairment mri Multimodal Neurofilament Proteins - blood Neurogranin - blood Neurology Neuropsychological Tests Neurosciences Neurosciences & Neurology Neurovetenskaper NMR Nuclear magnetic resonance p939 p967 Pathology Plasma Proteomics Psychiatric Status Rating Scales Research Design Research proposals v34 v55 Metabolomics Plasma Alzheimer’s disease Multimodal Magnetic resonance imaging Genomics DNA Proteomics Biomarkers Cerebrospinal fluid
ISSN:	1758-9193, 1758-9193
Online Access:	Get full text
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