Global burden of childhood pneumonia and diarrhoea

Diarrhoea and pneumonia are the leading infectious causes of childhood morbidity and mortality. We comprehensively reviewed the epidemiology of childhood diarrhoea and pneumonia in 2010–11 to inform the planning of integrated control programmes for both illnesses. We estimated that, in 2010, there w...

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Vydáno v:	The Lancet (British edition) Ročník 381; číslo 9875; s. 1405 - 1416
Hlavní autoři:	Walker, Christa L Fischer, Rudan, Igor, Liu, Li, Nair, Harish, Theodoratou, Evropi, Bhutta, Zulfiqar A, O'Brien, Katherine L, Campbell, Harry, Black, Robert E
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	England Elsevier Ltd 20.04.2013 Elsevier Limited
Témata:	Age Breast feeding Breastfeeding & lactation Child Child mortality Childhood Children Children & youth death Diarrhea Diarrhea - epidemiology Diarrhea - prevention & control Disease Epidemiology Estimates Fatalities Female Global Health Haemophilus influenzae Hospitals Humans Illnesses Immunization Incidence Influenza Integrated control Internal Medicine Low income groups Malnutrition Morbidity Mortality nutrient deficiencies Nutrient deficiency Pathogens planning Pneumonia Pneumonia - epidemiology Pneumonia - prevention & control Pneumonia - virology Risk analysis Risk Factors Risk sharing Rotavirus Rotavirus Infections - epidemiology Series Streptococcus infections Streptococcus pneumoniae Studies Undernutrition Vaccines zinc
ISSN:	0140-6736, 1474-547X, 1474-547X
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Shrnutí:	Diarrhoea and pneumonia are the leading infectious causes of childhood morbidity and mortality. We comprehensively reviewed the epidemiology of childhood diarrhoea and pneumonia in 2010–11 to inform the planning of integrated control programmes for both illnesses. We estimated that, in 2010, there were 1·731 billion episodes of diarrhoea (36 million of which progressed to severe episodes) and 120 million episodes of pneumonia (14 million of which progressed to severe episodes) in children younger than 5 years. We estimated that, in 2011, 700 000 episodes of diarrhoea and 1·3 million of pneumonia led to death. A high proportion of deaths occurs in the first 2 years of life in both diseases—72% for diarrhoea and 81% for pneumonia. The epidemiology of childhood diarrhoea and that of pneumonia overlap, which might be partly because of shared risk factors, such as undernutrition, suboptimum breastfeeding, and zinc deficiency. Rotavirus is the most common cause of vaccine-preventable severe diarrhoea (associated with 28% of cases), and Streptococcus pneumoniae (18·3%) of vaccine-preventable severe pneumonia. Morbidity and mortality from childhood pneumonia and diarrhoea are falling, but action is needed globally and at country level to accelerate the reduction.
Bibliografie:	http://dx.doi.org/10.1016/S0140-6736(13)60222-6 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Review-3 content type line 23 ObjectType-Article-2 ObjectType-Feature-1 ObjectType-Literature Review-3 These authors contributed equally
ISSN:	0140-6736 1474-547X 1474-547X
DOI:	10.1016/S0140-6736(13)60222-6