Complete genome sequence of a HPV31 isolate from laryngeal squamous cell carcinoma and biological consequences for p97 promoter activity

Human papillomavirus type 31, although detected less frequently than HPV types 16 and 18, is associated with head and neck squamous cell carcinomas. Previous studies suggest that polymorphisms in the long control region (LCR) may alter the oncogenic potential of the virus. This study reports the fir...

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Veröffentlicht in:	PloS one Jg. 16; H. 8; S. e0252524
Hauptverfasser:	Munsamy, Yuri, Seedat, Riaz Y., Sekee, Tumelo R., Bester, Phillip A., Burt, Felicity J.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	San Francisco Public Library of Science 25.08.2021 Public Library of Science (PLoS)
Schlagworte:	Analysis Binding sites Biology and life sciences Cancer Cell cycle Cloning Computer and Information Sciences DNA polymerase Engineering and Technology Enzymes Galactosidase Genetic aspects Genomes Head & neck cancer Head and neck Head and neck cancer Head and neck carcinoma Health sciences Hepatocellular carcinoma Human papillomavirus Laboratories Laryngeal cancer Medicine and Health Sciences Mutagenesis Mutants Mutation Nucleotide sequence Nucleotides Otolaryngology Papillomavirus infections Reporter gene Research and Analysis Methods Squamous cell carcinoma Transcription factors Variation Virology Viruses YY1 protein β-Galactosidase South Africa England United Kingdom > UK United States > US Finland
ISSN:	1932-6203, 1932-6203
Online-Zugang:	Volltext
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