Contributions of Age-Related Thymic Involution to Immunosenescence and Inflammaging

Immune system aging is characterized by the paradox of immunosenescence (insufficiency) and inflammaging (over-reaction), which incorporate two sides of the same coin, resulting in immune disorder. Immunosenescence refers to disruption in the structural architecture of immune organs and dysfunction...

Full description

Saved in:

Bibliographic Details
Published in:	Immunity & ageing Vol. 17; no. 1; pp. 2 - 17
Main Authors:	Thomas, Rachel, Wang, Weikan, Su, Dong-Ming
Format:	Journal Article
Language:	English
Published:	London BioMed Central 20.01.2020 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Adaptive immunity Age Age-related thymic involution Aging Antibodies Antigens Apoptosis Atrophy Biomedical and Life Sciences Biomedicine Cardiovascular diseases Cell cycle Central tolerance Clinical Nutrition Cyclin-dependent kinases Diseases Epigenetic inheritance Epigenetics Fibroblasts Genotype & phenotype Geriatrics/Gerontology Homeostasis Immune response Immune system Immunology Immunosenescence Immunosenescence and inflammaging Inflammation Kinases Lymphocytes Lymphocytes T Molecular modelling Money Negative selection and regulatory T (Treg) cell generation Phenotypes Public Health Recovery of function Rejuvenation Review Senescence Somatic cells Stem cells T cells Thymic aging Thymic involution Thymus Maryland Negative selection and regulatory T (Treg) cell generation Central tolerance Thymic aging Age-related thymic involution Immunosenescence and inflammaging Rejuvenation
ISSN:	1742-4933, 1742-4933
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!