Adverse effects and non-adherence to antihypertensive medications in University of Gondar Comprehensive Specialized Hospital

Background A considerable proportion of cardiovascular events could be attributed to poor adherence to antihypertensive medications. Adverse effects can be severe enough to affect adherence to antihypertensive medications. This study aimed to measure the contribution of adverse effects on antihypert...

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Vydané v:Clinical hypertension Ročník 25; číslo 1; s. 1 - 9
Hlavní autori: Gebreyohannes, Eyob Alemayehu, Bhagavathula, Akshaya Srikanth, Abebe, Tamrat Befekadu, Tefera, Yonas Getaye, Abegaz, Tadesse Melaku
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: London BioMed Central 15.01.2019
BioMed Central Ltd
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대한고혈압학회
Predmet:
Adherence
Adverse effects
Ambulatory care
Ambulatory care facilities
Analysis
Angiology
Antihypertensive agents
Antihypertensive medications
Antihypertensives
Blood pressure
Cardiology
Care and treatment
Complications and side effects
Data collection
Drug dosages
Drug therapy
Drugs
Ethiopia
Gondar
Heart attack
Hospitals
Hypertension
Medical records
Medicine
Medicine & Public Health
Mortality
Myalgia
Patient compliance
Patients
Prescription drugs
Qualitative research
Quality of life
Questionnaires
Risk factors
Sleep
Systematic review
내과학
Ethiopia
Hypertension
Adherence
Gondar
Adverse effects
Antihypertensive medications
Ethiopia
ISSN:2056-5909, 1342-2154, 2635-6325, 2056-5909
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Shrnutí:Background A considerable proportion of cardiovascular events could be attributed to poor adherence to antihypertensive medications. Adverse effects can be severe enough to affect adherence to antihypertensive medications. This study aimed to measure the contribution of adverse effects on antihypertensive medications adherence. Methods The study was conducted from May 1 to June 30, 2017, at the ambulatory clinic of University of Gondar Comprehensive Specialized Hospital (UOGCSH) in Gondar town. A binary logistic regression was performed to determine the significance of the association between adverse effects and adherence to antihypertensive medications. An institution-based cross-sectional study was conducted by administering a questionnaire to hypertensive patients who came for follow-up at the ambulatory clinic of UOGCSH. Level of adherence to antihypertensive medications was used as outcome measure. Results A total of 249 patients were included in the final analysis with a mean age of 56.51 years and a female majority (53%). The following variables were identified as predictors of poor adherence: tiredness [AOR (95% CI): 3.802 (1.723–8.391), p  = 0.001], muscle pain [AOR (95% CI): 5.199 (1.407–19.214), p  = 0.013], poor sleep [AOR (95% CI): 4.891 (1.578–15.160), p  = 0.006] and, believing that the symptoms were caused by antihypertensive medications [AOR (95% CI): 3.249 (1.248–8.456), p  = 0.016]. Conclusion Adverse effect significantly contributes to antihypertensive medication non-adherence among hypertensive patients.
Bibliografia:ObjectType-Article-1
SourceType-Scholarly Journals-1
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https://clinicalhypertension.biomedcentral.com/track/pdf/10.1186/s40885-018-0104-6
ISSN:2056-5909
1342-2154
2635-6325
2056-5909
DOI:10.1186/s40885-018-0104-6