Validation of a high performance functional assay for individual radiosensitivity in pediatric oncology: a prospective cohort study (ARPEGE)

Background Approximately 900 children/adolescents are treated with radiotherapy (RT) every year in France. However, among the 80% of survivors, the cumulative incidence of long-term morbidity – including second malignancies - reach 73.4% thirty years after the cancer diagnosis. Identifying a priori...

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Bibliographic Details
Published in:	BMC cancer Vol. 18; no. 1; pp. 719 - 6
Main Authors:	Bernier-chastagner, Valérie, Hettal, Liza, Gillon, Véronique, Fernandes, Laurinda, Huin-schohn, Cécile, Vazel, Marion, Tosti, Priscillia, Salleron, Julia, François, Aurélie, Cérimèle, Elise, Perreira, Sandrine, Peiffert, Didier, Chastagner, Pascal, Vogin, Guillaume
Format:	Journal Article
Language:	English
Published:	London BioMed Central 06.07.2018 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Adolescent Biomarker Biomedical and Life Sciences Biomedicine Brain cancer Cancer in children Cancer Research Cancer therapies Care and treatment Child Cohort analysis Deoxyribonucleic acid Diagnosis DNA DNA repair Fibroblasts Health Promotion and Disease Prevention Hematology Humans Medical and radiation oncology Medical diagnosis Medicine/Public Health Metabolism Morbidity Neoplasms - radiotherapy Oncology Pediatric oncology Pediatrics Predictive assay Prospective Studies Proteins Radiation therapy Radiation Tolerance Radiosensitivity Radiotherapy Safety and security measures Study Protocol Surgical Oncology Teenagers Toxicity France Predictive assay Pediatric oncology Biomarker Radiosensitivity Radiotherapy Toxicity
ISSN:	1471-2407, 1471-2407
Online Access:	Get full text
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