Anticancer effect of berberine based on experimental animal models of various cancers: a systematic review and meta-analysis

Background Numerous studies have explored the anti-tumor effect of berberine (BBR), but little clinical evidence guides the use of BBR in cancer patients. Objectives Our aim was to investigate the impact of BBR on various cancers in healthy animals to promote the transformation from bench to bed. Se...

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Bibliographic Details
Published in:	BMC cancer Vol. 19; no. 1; pp. 589 - 20
Main Authors:	Xu, Jianhao, Long, Yuming, Ni, Liwei, Yuan, Xuya, Yu, Na, Wu, Runhong, Tao, Jialong, Zhang, Yusong
Format:	Journal Article
Language:	English
Published:	London BioMed Central 17.06.2019 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Analysis Angiogenesis Angiogenesis Inhibitors - administration & dosage Angiogenesis Inhibitors - adverse effects Angiogenesis Inhibitors - therapeutic use Animal models Animals Antineoplastic Agents - administration & dosage Antineoplastic Agents - adverse effects Antineoplastic Agents - therapeutic use Berberine Berberine - administration & dosage Berberine - adverse effects Berberine - therapeutic use Berberis - chemistry Bias Biliary tract cancer Biomedical and Life Sciences Biomedicine Body Weight Breast cancer Cancer Cancer patients Cancer Research Cancer treatment Carcinoma Care and treatment Cholangiocarcinoma Colorectal cancer Colorectal carcinoma Cricetinae Disease Models, Animal Dogs Dose-Response Relationship, Drug Endometrial cancer Endometrium Esophageal cancer Esophagus Experimental animals Gastric cancer Gastrointestinal diseases Guinea Pigs Haplorhini Health aspects Health Promotion and Disease Prevention Horses Humans Liver Liver cancer Lung cancer Lung carcinoma Medical and radiation oncology Medical research Medicine/Public Health Meta-analysis Mice Nasopharyngeal carcinoma Neoplasms - drug therapy Neoplasms - metabolism Nutrition research Oncology Oral cancer Phytotherapy Plant Extracts - therapeutic use Practice guidelines (Medicine) Rabbits Rats Research Article Sarcoma Sheep Software Statistical analysis Studies Surgical Oncology Systematic review Throat cancer Tongue cancer Traditional Chinese medicine Tumor Burden Tumors Uterine cancer Berberine Experimental animals Cancer Meta-analysis
ISSN:	1471-2407, 1471-2407
Online Access:	Get full text
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