Melatonin plays critical role in mesenchymal stem cell-based regenerative medicine in vitro and in vivo

Although stem cells have emerged as promising sources for regenerative medicine, there are many potential safety hazards for their clinical application, including tumorigenicity, an availability shortage, senescence, and sensitivity to toxic environments. Mesenchymal stem cells (MSCs) have various a...

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Bibliographic Details
Published in:	Stem cell research & therapy Vol. 10; no. 1; pp. 13 - 11
Main Authors:	Hu, Chenxia, Li, Lanjuan
Format:	Journal Article
Language:	English
Published:	London BioMed Central 11.01.2019 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Apoptosis Biomaterials Biomedical and Life Sciences Biomedical Engineering and Bioengineering Biomedical materials Bone marrow Cell Biology Cell Proliferation - genetics Cytokines Embryo cells Embryonic Stem Cells - metabolism Gene expression Humans In vitro In vivo Induced Pluripotent Stem Cells - metabolism Ischemia Life Sciences Medicine Melatonin Melatonin - metabolism Mesenchymal stem cell Mesenchymal Stem Cell Transplantation Mesenchymal Stem Cells - metabolism Mesenchyme Oxidation Oxidative stress Physiology Pineal gland Pluripotency Protection Reactive oxygen species Regenerative Medicine Regenerative Medicine/Tissue Engineering Review Senescence Sepsis Stem Cells Transplantation Tumorigenicity Mesenchymal stem cell In vivo Therapy Melatonin Regenerative medicine In vitro Protection
ISSN:	1757-6512, 1757-6512
Online Access:	Get full text
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