Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola Ça Suffit!)

rVSV-ZEBOV is a recombinant, replication competent vesicular stomatitis virus-based candidate vaccine expressing a surface glycoprotein of Zaire Ebolavirus. We tested the effect of rVSV-ZEBOV in preventing Ebola virus disease in contacts and contacts of contacts of recently confirmed cases in Guinea...

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Bibliographic Details
Published in:	The Lancet (British edition) Vol. 389; no. 10068; pp. 505 - 518
Main Authors:	Henao-Restrepo, Ana Maria, Camacho, Anton, Longini, Ira M, Watson, Conall H, Edmunds, W John, Egger, Matthias, Carroll, Miles W, Dean, Natalie E, Diatta, Ibrahima, Doumbia, Moussa, Draguez, Bertrand, Duraffour, Sophie, Enwere, Godwin, Grais, Rebecca, Gunther, Stephan, Gsell, Pierre-Stéphane, Hossmann, Stefanie, Watle, Sara Viksmoen, Kondé, Mandy Kader, Kéïta, Sakoba, Kone, Souleymane, Kuisma, Eewa, Levine, Myron M, Mandal, Sema, Mauget, Thomas, Norheim, Gunnstein, Riveros, Ximena, Soumah, Aboubacar, Trelle, Sven, Vicari, Andrea S, Røttingen, John-Arne, Kieny, Marie-Paule
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 04.02.2017 Elsevier Limited Elsevier
Subjects:	Adolescent Adult Anaphylaxis Breast feeding Child Children Clinical trials Cluster Analysis Clusters Complications Contact Tracing Correlation coefficient Correlation coefficients Disease Disease prevention Ebola Vaccines Ebola virus Ebolavirus Epidemics Ethics Female Glycoproteins Guinea Headache Hemorrhagic Fever, Ebola - diagnosis Hemorrhagic Fever, Ebola - prevention & control Hemorrhagic Fever, Ebola - transmission Humans Immunization Influenza Internal Medicine Male Membrane Glycoproteins Middle Aged Muscle pain Muscles Muscular fatigue Pain Public health R&D Randomization Research & development Stomatitis Treatment Outcome Vaccination Vaccine efficacy Vaccines Vesiculovirus Viral diseases Young Adult Guinea Africa
ISSN:	0140-6736, 1474-547X, 1474-547X
Online Access:	Get full text
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