Metaproteomics reveals persistent and phylum-redundant metabolic functional stability in adult human gut microbiomes of Crohn’s remission patients despite temporal variations in microbial taxa, genomes, and proteomes

Background The gut microbiome plays a fundamental role in the human host’s overall health by contributing key biological functions such as expanded metabolism and pathogen defense/immune control. In a healthy individual, the gut microbiome co-exists within the human host in a symbiotic, non-inflamma...

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Bibliographic Details
Published in:	Microbiome Vol. 7; no. 1; pp. 18 - 15
Main Authors:	Blakeley-Ruiz, J. Alfredo, Erickson, Alison R., Cantarel, Brandi L., Xiong, Weili, Adams, Rachel, Jansson, Janet K., Fraser, Claire M., Hettich, Robert L.
Format:	Journal Article
Language:	English
Published:	London BioMed Central 11.02.2019 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Acetylglucosamine - analysis Adult Amino acids Bacteria - genetics Bacteria - metabolism BASIC BIOLOGICAL SCIENCES Bioinformatics Biomedical and Life Sciences Biomedicine Crohn Disease - microbiology Crohn Disease - surgery Crohn's disease Cytidine Monophosphate N-Acetylneuraminic Acid - analysis Digestive system E coli Enzymes Fatty acids Fatty Acids, Volatile - analysis Feces - microbiology Female Fermentation Food Food products Gastrointestinal Microbiome - genetics Gastrointestinal Microbiome - physiology Genes Genomes Genomics Gut microbiome Health aspects Human microbiome Humans Inflammation Inflammatory bowel disease Intestinal microflora Longitudinal analyses Male Medical Microbiology Metabolism Metaproteomics Microbial Ecology Microbial Genetics and Genomics Microbial metabolic function Microbiology Microbiomes Microbiota Microbiota (Symbiotic organisms) Middle Aged Pathogens Phenotypes Physiological aspects Product enhancement Proteins Proteome - metabolism Proteomics Remission Retirement benefits RNA, Ribosomal, 16S - genetics Studies Surgery Temporal variations Virology Human microbiome Microbial metabolic function Metaproteomics Longitudinal analyses Gut microbiome Crohn’s disease
ISSN:	2049-2618, 2049-2618
Online Access:	Get full text
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