Chemokines modulate glycan binding and the immunoregulatory activity of galectins

Galectins are versatile glycan-binding proteins involved in immunomodulation. Evidence suggests that galectins can control the immunoregulatory function of cytokines and chemokines through direct binding. Here, we report on an inverse mechanism in which chemokines control the immunomodulatory functi...

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Bibliographic Details
Published in:	Communications biology Vol. 4; no. 1; pp. 1415 - 11
Main Authors:	Sanjurjo, Lucía, Schulkens, Iris A., Touarin, Pauline, Heusschen, Roy, Aanhane, Ed, Castricum, Kitty C. M., De Gruijl, Tanja D., Nilsson, Ulf J., Leffler, Hakon, Griffioen, Arjan W., Elantak, Latifa, Koenen, Rory R., Thijssen, Victor L. J. L.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 20.12.2021 Nature Publishing Group Nature Portfolio
Subjects:	13/2 13/21 13/31 631/250/1932 631/535/878/1263 631/80/221 82/103 82/58 Affinity Apoptosis Basic Medicine Binding sites Biology Biomedical and Life Sciences CD4 antigen CD8 antigen Chemokine CXCL5 - metabolism Chemokines Cytokines Galectin 1 - metabolism Galectin-1 Galectin-9 Galectins - metabolism Humans Immunologi inom det medicinska området (Här ingår: Cell- och immunterapi) Immunology in the Medical Area (including Cell and Immunotherapy) Immunomodulation Immunoregulation Jurkat Cells Life Sciences Lymphocytes Lymphocytes T Medical and Health Sciences Medicin och hälsovetenskap Medicinska och farmaceutiska grundvetenskaper Platelet Factor 4 - metabolism Polysaccharides - metabolism
ISSN:	2399-3642, 2399-3642
Online Access:	Get full text
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