A divergent protein kinase A regulatory subunit essential for morphogenesis of the human pathogen Leishmania

Parasitic protozoa of the genus Leishmania cycle between the phagolysosome of mammalian macrophages, where they reside as rounded intracellular amastigotes, and the midgut of female sand flies, which they colonize as elongated extracellular promastigotes. Previous studies indicated that protein kina...

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Bibliographic Details
Published in:	PLoS pathogens Vol. 20; no. 3; p. e1012073
Main Authors:	Fischer Weinberger, Renana, Bachmaier, Sabine, Ober, Veronica, Githure, George B., Dandugudumula, Ramu, Phan, Isabelle Q., Almoznino, Michal, Polatoglou, Eleni, Tsigankov, Polina, Nitzan Koren, Roni, Myler, Peter J., Boshart, Michael, Zilberstein, Dan
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 01.03.2024 Public Library of Science (PLoS)
Subjects:	Amastigotes Amino acids Analysis Antibodies Axons Biology and Life Sciences Cell size Composition Cyclic adenylic acid Elongation Energy transfer Eukaryotes Homology Kinases Leishmania Leishmaniasis Localization Macrophages Mammals Microscopy Microtubules Midgut Morphogenesis Nucleoside analogs Parasitic diseases Phosphorylation Prevention Promastigotes Protein kinase A Protein kinases Proteins Protozoa Regulation Research and Analysis Methods Risk factors Signal transduction Tethering United States Israel
ISSN:	1553-7374, 1553-7366, 1553-7374
Online Access:	Get full text
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