Protein quantitative trait locus analysis in African American and non-Hispanic White individuals

Background Substantial efforts have been dedicated to exploring the link between genetic regulation and the proteome, informing studies of complex trait mechanisms. Most of these efforts have been limited to populations of European ancestry. Results We conduct an Olink protein quantitative trait loc...

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Vydané v:	Genome Biology Ročník 26; číslo 1; s. 200
Hlavní autori:	Cai, Yanwei, Johnson, Mari, Haessler, Jeffrey, Molstad, Aaron J., Hwang, Shih-Jen, Joehanes, Roby, Murabito, Joanne M., Tahir, Usman A., Franceschini, Nora, Gerszten, Robert E., Sun, Wei, Levy, Daniel, Raffield, Laura M., Kooperberg, Charles, Hsu, Li, Reiner, Alexander P.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	London BioMed Central 10.07.2025 Springer Nature B.V BMC
Predmet:	Adult ancestry Animal Genetics and Genomics Association analysis Bioinformatics Biomarkers Biomedical and Life Sciences Black or African American - genetics Chromosome 19 chromosomes disease susceptibility Evolutionary Biology Female Genes Genome-Wide Association Study Genomic analysis Human Genetics Humans Insights from trans-ancestral association study leukocytes Life Sciences Male Microbial Genetics and Genomics Middle Aged multigene family Olink Plant Genetics and Genomics Polymorphism, Single Nucleotide Proteins proteome Proteomes Proteomics Quantitative Trait Loci Statistical analysis statistics White - genetics Whole genome sequencing Whole genome sequencing Olink Proteomics
ISSN:	1474-760X, 1474-7596, 1474-760X
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