A road map for understanding molecular and genetic determinants of osteoporosis

Osteoporosis is a highly prevalent disorder characterized by low bone mineral density and an increased risk of fracture, termed osteoporotic fracture. Notably, bone mineral density, osteoporosis and osteoporotic fracture are highly heritable; however, determining the genetic architecture, and especi...

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Bibliographic Details
Published in:	Nature reviews. Endocrinology Vol. 16; no. 2; pp. 91 - 103
Main Authors:	Yang, Tie-Lin, Shen, Hui, Liu, Anqi, Dong, Shan-Shan, Zhang, Lei, Deng, Fei-Yan, Zhao, Qi, Deng, Hong-Wen
Format:	Journal Article
Language:	English
Published:	England Nature Publishing Group 01.02.2020
Subjects:	Bone density Bone Density - physiology Bone mineral density Epigenomics - methods Fractures Fractures, Bone - genetics Fractures, Bone - metabolism Fractures, Bone - prevention & control Genome-wide association studies Genome-Wide Association Study - methods Genomes Genomics Genomics - methods Humans Integration Metabolomics Metabolomics - methods Molecular modelling Osteoporosis Osteoporosis - epidemiology Osteoporosis - genetics Osteoporosis - metabolism Pathogenesis Proteomics Proteomics - methods
ISSN:	1759-5029, 1759-5037, 1759-5037
Online Access:	Get full text
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