Studies of Reservoir Hosts for Marburg Virus

To determine reservoir hosts for Marburg virus (MARV), we examined the fauna of a mine in northeastern Democratic Republic of the Congo. The mine was associated with a protracted outbreak of Marburg hemorrhagic fever during 1998-2000. We found MARV nucleic acid in 12 bats, comprising 3.0%-3.6% of 2...

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Vydáno v:Emerging infectious diseases Ročník 13; číslo 12; s. 1847 - 1851
Hlavní autoři: Swanepoel, Robert, Smit, Sheilagh B., Rollin, Pierre E., Formenty, Pierre, Leman, Patricia A., Kemp, Alan, Burt, Felicity J., Grobbelaar, Antoinette A., Croft, Janice, Bausch, Daniel G., Zeller, Hervé, Leirs, Herwig, Braack, L.E.O., Libande, Modeste L., Zaki, Sherif, Nichol, Stuart T., Ksiazek, Thomas G., Paweska, Janusz T.
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States U.S. National Center for Infectious Diseases 01.12.2007
Centers for Disease Control and Prevention
Témata:
Animals
Antibodies, Viral - analysis
Antibodies, Viral - immunology
Bats
Chiroptera - classification
Chiroptera - immunology
Chiroptera - virology
Democratic Republic of Congo
Democratic Republic of the Congo
Genetic aspects
Marburg virus
Marburg virus disease
Marburgvirus - genetics
Marburgvirus - immunology
Marburgvirus - isolation & purification
Mining
Nucleic acids
Phylogeny
reservoir hosts
RNA, Viral - genetics
RNA, Viral - isolation & purification
Democratic Republic of the Congo
United States
ISSN:1080-6040, 1080-6059
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Shrnutí:To determine reservoir hosts for Marburg virus (MARV), we examined the fauna of a mine in northeastern Democratic Republic of the Congo. The mine was associated with a protracted outbreak of Marburg hemorrhagic fever during 1998-2000. We found MARV nucleic acid in 12 bats, comprising 3.0%-3.6% of 2 species of insectivorous bat and 1 species of fruit bat. We found antibody to the virus in the serum of 9.7% of 1 of the insectivorous species and in 20.5% of the fruit bat species, but attempts to isolate virus were unsuccessful.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1080-6040
1080-6059
DOI:10.3201/eid1312.071115