A recombinant Yellow Fever 17D vaccine expressing Lassa virus glycoproteins

The Yellow Fever Vaccine 17D (YFV17D) has been used as a vector for the Lassa virus glycoprotein precursor (LASV-GPC) resulting in construction of YFV17D/LASV-GPC recombinant virus. The virus was replication-competent and processed the LASV-GPC in cell cultures. The recombinant replicated poorly in...

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Bibliographic Details
Published in:	Virology (New York, N.Y.) Vol. 345; no. 2; pp. 299 - 304
Main Authors:	Bredenbeek, Peter J., Molenkamp, Richard, Spaan, Willy J.M., Deubel, Vincent, Marianneau, Phillippe, Salvato, Maria S., Moshkoff, Dmitry, Zapata, Juan, Tikhonov, Ilia, Patterson, Jean, Carrion, Ricardo, Ticer, Anysha, Brasky, Kathleen, Lukashevich, Igor S.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 20.02.2006
Subjects:	Animals genetic vectors glycoproteins Glycoproteins - genetics Glycoproteins - metabolism Guinea Pigs human health Humans Lassa Fever - prevention & control Lassa mammarenavirus Lassa virus Lassa virus - genetics Lassa virus - immunology Lassa virus - metabolism recombinant fusion proteins Recombinant vaccine vaccines Vaccines, Synthetic - administration & dosage Vaccines, Synthetic - genetics Vaccines, Synthetic - metabolism viral antibodies viral proteins Viral Vaccines - administration & dosage Viral Vaccines - genetics Viral Vaccines - metabolism Yellow and Lassa Fevers yellow fever Yellow Fever - prevention & control Yellow Fever Vaccine - administration & dosage Yellow Fever Vaccine - genetics Yellow Fever Vaccine - metabolism Yellow fever virus Yellow fever virus - immunology YFV17D vaccine Africa YFV17D vaccine Recombinant vaccine Yellow and Lassa Fevers
ISSN:	0042-6822, 1096-0341
Online Access:	Get full text
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