Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort

A genome-wide, whole brain approach to investigate genetic effects on neuroimaging phenotypes for identifying quantitative trait loci is described. The Alzheimer's Disease Neuroimaging Initiative 1.5 T MRI and genetic dataset was investigated using voxel-based morphometry (VBM) and FreeSurfer p...

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Vydáno v:	NeuroImage (Orlando, Fla.) Ročník 53; číslo 3; s. 1051 - 1063
Hlavní autoři:	Shen, Li, Kim, Sungeun, Risacher, Shannon L., Nho, Kwangsik, Swaminathan, Shanker, West, John D., Foroud, Tatiana, Pankratz, Nathan, Moore, Jason H., Sloan, Chantel D., Huentelman, Matthew J., Craig, David W., DeChairo, Bryan M., Potkin, Steven G., Jack, Clifford R., Weiner, Michael W., Saykin, Andrew J.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Elsevier Inc 15.11.2010 Elsevier Limited
Témata:	Aged Alzheimer Disease - genetics Alzheimer's disease Apolipoproteins E - genetics Automation Cluster Analysis Cognition Disorders - genetics Databases, Factual Female Genetic Predisposition to Disease Genetics Genome-Wide Association Study Genomes Genomics Genotype Genotype & phenotype Humans Magnetic Resonance Imaging Male Medical imaging Phenotype Polymorphism, Single Nucleotide Public private partnerships Quantitative Trait Loci Studies
ISSN:	1053-8119, 1095-9572, 1095-9572
On-line přístup:	Získat plný text
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