Interepidemic Rift Valley Fever Virus Seropositivity, Northeastern Kenya

Most outbreaks of Rift Valley fever (RVF) occur in remote locations after floods. To determine environmental risk factors and long-term sequelae of human RVF, we examined rates of previous Rift Valley fever virus (RVFV) exposure by age and location during an interepidemic period in 2006. In a random...

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Veröffentlicht in:Emerging infectious diseases Jg. 14; H. 8; S. 1240 - 1246
Hauptverfasser: LaBeaud, A. Desiree, Muchiri, Eric M., Ndzovu, Malik, Mwanje, Mariam T., Muiruri, Samuel, Peters, Clarence J., King, Charles H.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States U.S. National Center for Infectious Diseases 01.08.2008
Centers for Disease Control and Prevention
Schlagworte:
Adolescent
Adult
Aged
Antibodies, Viral - blood
arboviruses
bioterrorism
Bunyaviridae
Child
Child, Preschool
Disease Outbreaks
Enzyme-linked immunosorbent assay
Female
hemorrhagic fevers/viral
Housing
Humans
Immunoglobulin G
Immunoglobulin G - blood
Infant
Kenya
Kenya - epidemiology
Male
Middle Aged
Odds Ratio
Rift Valley fever
Rift Valley Fever - blood
Rift Valley Fever - epidemiology
Rift Valley Fever - immunology
Rift Valley fever virus
Risk Factors
Rural Population
Seroepidemiologic Studies
Surveys
Kenya
ISSN:1080-6040, 1080-6059, 1080-6059
Online-Zugang:Volltext
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Zusammenfassung:Most outbreaks of Rift Valley fever (RVF) occur in remote locations after floods. To determine environmental risk factors and long-term sequelae of human RVF, we examined rates of previous Rift Valley fever virus (RVFV) exposure by age and location during an interepidemic period in 2006. In a randomized household cluster survey in 2 areas of Ijara District, Kenya, we examined 248 residents of 2 sublocations, Gumarey (village) and Sogan-Godud (town). Overall, the RVFV seropositivity rate was 13% according to immunoglobulin G ELISA; evidence of interepidemic RVFV transmission was detected. Increased seropositivity was found among older persons, those who were male, those who lived in the rural village (Gumarey), and those who had disposed of animal abortus. Rural Gumarey reported more mosquito and animal exposure than Sogan-Godud. Seropositive persons were more likely to have visual impairment and retinal lesions; other physical findings did not differ.
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1080-6040
1080-6059
1080-6059
DOI:10.3201/eid1408.080082