Differences in Neuropathogenesis of Encephalitic California Serogroup Viruses
The California serogroup of orthobunyaviruses comprises a group of mosquitoborne viruses, including La Crosse (LACV), snowshoe hare (SSHV), Tahyna (TAHV), Jamestown Canyon (JCV), and Inkoo (INKV) viruses, that cause neurologic disease in humans of differing ages with varying incidences. To determine...
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| Published in: | Emerging infectious diseases Vol. 25; no. 4; pp. 728 - 738 |
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| Main Authors: | , , |
| Format: | Journal Article |
| Language: | English |
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United States
U.S. National Center for Infectious Diseases
01.04.2019
Centers for Disease Control and Prevention |
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| ISSN: | 1080-6040, 1080-6059, 1080-6059 |
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| Abstract | The California serogroup of orthobunyaviruses comprises a group of mosquitoborne viruses, including La Crosse (LACV), snowshoe hare (SSHV), Tahyna (TAHV), Jamestown Canyon (JCV), and Inkoo (INKV) viruses, that cause neurologic disease in humans of differing ages with varying incidences. To determine how the pathogenesis of these viruses differs, we compared their ability to induce disease in mice and replicate and induce cell death in vitro. In mice, LACV, TAHV, and SSHV induced neurologic disease after intraperitoneal and intranasal inoculation, and JCV induced disease only after intranasal inoculation. INKV rarely induced disease, which correlated with less viral antigen in the brain than the other viruses. In vitro, all viruses replicated to high titers; however, LACV, SSHV, and TAHV induced high cell death, whereas JCV and INKV did not. Results demonstrated that CSG viruses differ in neuropathogenesis in vitro and in vivo, which correlates with the differences in pathogenesis reported in humans. |
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| AbstractList | The California serogroup of orthobunyaviruses comprises a group of mosquitoborne viruses, including La Crosse (LACV), snowshoe hare (SSHV), Tahyna (TAHV), Jamestown Canyon (JCV), and Inkoo (INKV) viruses, that cause neurologic disease in humans of differing ages with varying incidences. To determine how the pathogenesis of these viruses differs, we compared their ability to induce disease in mice and replicate and induce cell death in vitro. In mice, LACV, TAHV, and SSHV induced neurologic disease after intraperitoneal and intranasal inoculation, and JCV induced disease only after intranasal inoculation. INKV rarely induced disease, which correlated with less viral antigen in the brain than the other viruses. In vitro, all viruses replicated to high titers; however, LACV, SSHV, and TAHV induced high cell death, whereas JCV and INKV did not. Results demonstrated that CSG viruses differ in neuropathogenesis in vitro and in vivo, which correlates with the differences in pathogenesis reported in humans. The California serogroup of orthobunyaviruses comprises a group of mosquitoborne viruses, including La Crosse (LACV), snowshoe hare (SSHV), Tahyna (TAHV), Jamestown Canyon (JCV), and Inkoo (INKV) viruses, that cause neurologic disease in humans of differing ages with varying incidences. To determine how the pathogenesis of these viruses differs, we compared their ability to induce disease in mice and replicate and induce cell death in vitro. In mice, LACV, TAHV, and SSHV induced neurologic disease after intraperitoneal and intranasal inoculation, and JCV induced disease only after intranasal inoculation. INKV rarely induced disease, which correlated with less viral antigen in the brain than the other viruses. In vitro, all viruses replicated to high titers; however, LACV, SSHV, and TAHV induced high cell death, whereas JCV and INKV did not. Results demonstrated that CSG viruses differ in neuropathogenesis in vitro and in vivo, which correlates with the differences in pathogenesis reported in humans.The California serogroup of orthobunyaviruses comprises a group of mosquitoborne viruses, including La Crosse (LACV), snowshoe hare (SSHV), Tahyna (TAHV), Jamestown Canyon (JCV), and Inkoo (INKV) viruses, that cause neurologic disease in humans of differing ages with varying incidences. To determine how the pathogenesis of these viruses differs, we compared their ability to induce disease in mice and replicate and induce cell death in vitro. In mice, LACV, TAHV, and SSHV induced neurologic disease after intraperitoneal and intranasal inoculation, and JCV induced disease only after intranasal inoculation. INKV rarely induced disease, which correlated with less viral antigen in the brain than the other viruses. In vitro, all viruses replicated to high titers; however, LACV, SSHV, and TAHV induced high cell death, whereas JCV and INKV did not. Results demonstrated that CSG viruses differ in neuropathogenesis in vitro and in vivo, which correlates with the differences in pathogenesis reported in humans. |
| Audience | Professional Academic |
| Author | Winkler, Clayton W. Peterson, Karin E. Evans, Alyssa B. |
| Author_xml | – sequence: 1 givenname: Alyssa B. surname: Evans fullname: Evans, Alyssa B. – sequence: 2 givenname: Clayton W. surname: Winkler fullname: Winkler, Clayton W. – sequence: 3 givenname: Karin E. surname: Peterson fullname: Peterson, Karin E. |
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| Cites_doi | 10.3201/eid2205.151015 10.1093/oxfordjournals.aje.a121178 10.4269/ajtmh.15-0196 10.4269/ajtmh.1999.60.806 10.1128/CVI.00288-07 10.1186/1743-422X-8-135 10.4269/ajtmh.1972.21.985 10.7589/2015-01-021 10.1089/vbz.2013.1360 10.7589/0090-3558-23.2.199 10.1089/vbz.2007.0169 10.1542/peds.2014-0498 10.1016/j.virol.2017.09.022 10.1007/s00436-008-1064-7 10.4269/ajtmh.2010.09-0688 10.7589/0090-3558-9.3.245 10.1007/s00401-015-1433-0 10.1186/s12974-017-0836-3 10.4269/ajtmh.1972.21.476 10.4269/ajtmh.1975.24.1006 10.1128/JVI.01933-06 10.1038/nrmicro3332 10.1139/m81-187 10.4269/ajtmh.2006.74.1078 10.1093/ofid/ofx150 10.1007/s13365-016-0428-5 10.4269/ajtmh.14-0291 10.1016/j.ajpath.2011.04.011 10.4269/ajtmh.1986.35.1285 10.4049/jimmunol.1601949 10.4269/ajtmh.1989.40.428 10.4269/ajtmh.1984.33.1218 10.14745/ccdr.v41i06a01 10.4269/ajtmh.1964.13.738 10.1093/jmedent/23.6.588 10.1186/1743-422X-5-25 10.1016/j.virusres.2010.01.005 10.1089/vbz.2015.1865 10.1371/journal.pone.0006145 10.1128/JVI.01866-14 10.1186/1743-422X-8-136 |
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| Keywords | Inkoo virus viruses mouse model United States virus replication Tahyna virus La Crosse virus brain neuropathogenesis neurons C57BL/6 pathogenicity vector-borne infections mosquitoborne viruses California serogroup viruses encephalitis orthobunyaviruses snowshoe hare virus Jamestown Canyon virus |
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| References | Tyers (key-10.3201/eid2504.181016-201903171059-R23) 2015; 51 Butchi (key-10.3201/eid2504.181016-201903171059-R42) 2011; 179 Bennett (key-10.3201/eid2504.181016-201903171059-R40) 2011; 8 Gaensbauer (key-10.3201/eid2504.181016-201903171059-R5) 2014; 134 Haddow (key-10.3201/eid2504.181016-201903171059-R14) 2009; 4 Eldridge (key-10.3201/eid2504.181016-201903171059-R25) 1987; 23 key-10.3201/eid2504.181016-201903171059-R4 McFarlane (key-10.3201/eid2504.181016-201903171059-R20) 1981; 27 Sonnleitner (key-10.3201/eid2504.181016-201903171059-R35) 2014; 14 Heard (key-10.3201/eid2504.181016-201903171059-R18) 1990; 6 Kosoy (key-10.3201/eid2504.181016-201903171059-R10) 2016; 16 Andreadis (key-10.3201/eid2504.181016-201903171059-R33) 2008; 8 Winkler (key-10.3201/eid2504.181016-201903171059-R43) 2017; 198 Drebot (key-10.3201/eid2504.181016-201903171059-R1) 2015; 41 Clark (key-10.3201/eid2504.181016-201903171059-R15) 1986; 23 Campbell (key-10.3201/eid2504.181016-201903171059-R24) 1989; 40 Elliott (key-10.3201/eid2504.181016-201903171059-R37) 2014; 12 Taylor (key-10.3201/eid2504.181016-201903171059-R39) 2014; 88 Monath (key-10.3201/eid2504.181016-201903171059-R11) 1970; 92 Issel (key-10.3201/eid2504.181016-201903171059-R26) 1972; 21 Winkler (key-10.3201/eid2504.181016-201903171059-R45) 2015; 130 Srihongse (key-10.3201/eid2504.181016-201903171059-R27) 1984; 33 Kunz (key-10.3201/eid2504.181016-201903171059-R34) 1964; 13 Walters (key-10.3201/eid2504.181016-201903171059-R13) 1999; 60 Lau (key-10.3201/eid2504.181016-201903171059-R6) 2017; 4 Kuniholm (key-10.3201/eid2504.181016-201903171059-R36) 2006; 74 Pastula (key-10.3201/eid2504.181016-201903171059-R8) 2015; 93 Issel (key-10.3201/eid2504.181016-201903171059-R22) 1973; 9 Anderson (key-10.3201/eid2504.181016-201903171059-R19) 2015; 92 Boromisa (key-10.3201/eid2504.181016-201903171059-R16) 1986; 35 Pinger (key-10.3201/eid2504.181016-201903171059-R17) 1975; 24 Blakqori (key-10.3201/eid2504.181016-201903171059-R38) 2007; 81 Pastula (key-10.3201/eid2504.181016-201903171059-R9) 2016; 22 Jentes (key-10.3201/eid2504.181016-201903171059-R29) 2010; 83 Hughes (key-10.3201/eid2504.181016-201903171059-R30) 2017; 512 Bennett (key-10.3201/eid2504.181016-201903171059-R41) 2011; 8 Putkuri (key-10.3201/eid2504.181016-201903171059-R12) 2007; 14 Hubálek (key-10.3201/eid2504.181016-201903171059-R2) 2008; 103 Kilian (key-10.3201/eid2504.181016-201903171059-R7) 2010; 149 Putkuri (key-10.3201/eid2504.181016-201903171059-R3) 2016; 22 Berry (key-10.3201/eid2504.181016-201903171059-R21) 1977; 37 Walker (key-10.3201/eid2504.181016-201903171059-R28) 1993; 9 Winkler (key-10.3201/eid2504.181016-201903171059-R46) 2017; 14 Pantuwatana (key-10.3201/eid2504.181016-201903171059-R31) 1972; 21 Artsob (key-10.3201/eid2504.181016-201903171059-R32) 1983; 123 Bennett (key-10.3201/eid2504.181016-201903171059-R44) 2008; 5 |
| References_xml | – volume: 22 start-page: 810 year: 2016 ident: key-10.3201/eid2504.181016-201903171059-R3 article-title: Acute human Inkoo and Chatanga virus infections, Finland. publication-title: Emerg Infect Dis doi: 10.3201/eid2205.151015 – volume: 37 start-page: 494 year: 1977 ident: key-10.3201/eid2504.181016-201903171059-R21 article-title: Evidence for transovarial transmission of Jamestown Canyon virus in Ohio. publication-title: Mosq News – volume: 92 start-page: 40 year: 1970 ident: key-10.3201/eid2504.181016-201903171059-R11 article-title: Studies on California encephalitis in Minnesota. publication-title: Am J Epidemiol doi: 10.1093/oxfordjournals.aje.a121178 – volume: 93 start-page: 384 year: 2015 ident: key-10.3201/eid2504.181016-201903171059-R8 article-title: Jamestown Canyon virus disease in the United States—2000–2013. publication-title: Am J Trop Med Hyg doi: 10.4269/ajtmh.15-0196 – volume: 9 start-page: 131 year: 1993 ident: key-10.3201/eid2504.181016-201903171059-R28 article-title: Isolation of Jamestown Canyon and snowshoe hare viruses (California serogroup) from Aedes mosquitoes in western Massachusetts. publication-title: J Am Mosq Control Assoc – volume: 60 start-page: 806 year: 1999 ident: key-10.3201/eid2504.181016-201903171059-R13 article-title: Seroepidemiology of California and Bunyamwera serogroup (Bunyaviridae) virus infections in native populations of Alaska. publication-title: Am J Trop Med Hyg doi: 10.4269/ajtmh.1999.60.806 – volume: 14 start-page: 1555 year: 2007 ident: key-10.3201/eid2504.181016-201903171059-R12 article-title: Prevalence and protein specificity of human antibodies to Inkoo virus infection. publication-title: Clin Vaccine Immunol doi: 10.1128/CVI.00288-07 – volume: 8 start-page: 135 year: 2011 ident: key-10.3201/eid2504.181016-201903171059-R40 article-title: Tahyna virus genetics, infectivity, and immunogenicity in mice and monkeys. publication-title: Virol J doi: 10.1186/1743-422X-8-135 – volume: 21 start-page: 985 year: 1972 ident: key-10.3201/eid2504.181016-201903171059-R26 article-title: Serologic evidence of infections of white-tailed deer in Wisconsin with three California group arboviruses (La Crosse, trivittatus, and Jamestown Canyon). publication-title: Am J Trop Med Hyg doi: 10.4269/ajtmh.1972.21.985 – volume: 51 start-page: 769 year: 2015 ident: key-10.3201/eid2504.181016-201903171059-R23 article-title: Serologic survey of snowshoe hares (Lepus americanus) in the Greater Yellowstone Area for brucellosis, tularemia, and snowshoe hare virus. publication-title: J Wildl Dis doi: 10.7589/2015-01-021 – volume: 14 start-page: 272 year: 2014 ident: key-10.3201/eid2504.181016-201903171059-R35 article-title: Investigations on California serogroup orthobunyaviruses in the Tyrols: first description of Tahyna virus in the Alps. publication-title: Vector Borne Zoonotic Dis doi: 10.1089/vbz.2013.1360 – volume: 23 start-page: 199 year: 1987 ident: key-10.3201/eid2504.181016-201903171059-R25 article-title: Serological evidence of California serogroup virus activity in Oregon. publication-title: J Wildl Dis doi: 10.7589/0090-3558-23.2.199 – volume: 123 start-page: 277 year: 1983 ident: key-10.3201/eid2504.181016-201903171059-R32 article-title: Distribution of California serogroup viruses and virus infections in Canada. publication-title: Prog Clin Biol Res – volume: 8 start-page: 175 year: 2008 ident: key-10.3201/eid2504.181016-201903171059-R33 article-title: Isolations of Jamestown Canyon virus (Bunyaviridae: Orthobunyavirus) from field-collected mosquitoes (Diptera: Culicidae) in Connecticut, USA: a ten-year analysis, 1997-2006. publication-title: Vector Borne Zoonotic Dis doi: 10.1089/vbz.2007.0169 – volume: 134 start-page: e642 year: 2014 ident: key-10.3201/eid2504.181016-201903171059-R5 article-title: Neuroinvasive arboviral disease in the United States: 2003 to 2012. publication-title: Pediatrics doi: 10.1542/peds.2014-0498 – volume: 512 start-page: 201 year: 2017 ident: key-10.3201/eid2504.181016-201903171059-R30 article-title: Full genomic characterization of California serogroup viruses, genus Orthobunyavirus, family Peribunyaviridae including phylogenetic relationships. publication-title: Virology doi: 10.1016/j.virol.2017.09.022 – volume: 103 start-page: S29 year: 2008 ident: key-10.3201/eid2504.181016-201903171059-R2 article-title: Mosquito-borne viruses in Europe. publication-title: Parasitol Res doi: 10.1007/s00436-008-1064-7 – volume: 83 start-page: 388 year: 2010 ident: key-10.3201/eid2504.181016-201903171059-R29 article-title: Acute arboviral infections in Guinea, West Africa, 2006. publication-title: Am J Trop Med Hyg doi: 10.4269/ajtmh.2010.09-0688 – volume: 9 start-page: 245 year: 1973 ident: key-10.3201/eid2504.181016-201903171059-R22 article-title: Serologic evidence of infection of white-tailed deer in Texas with three California group arboviruses, (Jamestown Canyon, San Angelo, and Keystone). publication-title: J Wildl Dis doi: 10.7589/0090-3558-9.3.245 – volume: 130 start-page: 233 year: 2015 ident: key-10.3201/eid2504.181016-201903171059-R45 article-title: Capillaries in the olfactory bulb but not the cortex are highly susceptible to virus-induced vascular leak and promote viral neuroinvasion. publication-title: Acta Neuropathol doi: 10.1007/s00401-015-1433-0 – volume: 14 start-page: 62 year: 2017 ident: key-10.3201/eid2504.181016-201903171059-R46 article-title: Lymphocytes have a role in protection, but not in pathogenesis, during La Crosse Virus infection in mice. publication-title: J Neuroinflammation doi: 10.1186/s12974-017-0836-3 – volume: 21 start-page: 476 year: 1972 ident: key-10.3201/eid2504.181016-201903171059-R31 article-title: Experimental infection of chipmunks and squirrels with La Crosse and Trivittatus viruses and biological transmission of La Crosse virus by Aedes triseriatus. publication-title: Am J Trop Med Hyg doi: 10.4269/ajtmh.1972.21.476 – volume: 24 start-page: 1006 year: 1975 ident: key-10.3201/eid2504.181016-201903171059-R17 article-title: Trivittatus virus infections in wild mammals and sentinel rabbits in central Iowa. publication-title: Am J Trop Med Hyg doi: 10.4269/ajtmh.1975.24.1006 – volume: 81 start-page: 4991 year: 2007 ident: key-10.3201/eid2504.181016-201903171059-R38 article-title: La Crosse bunyavirus nonstructural protein NSs serves to suppress the type I interferon system of mammalian hosts. publication-title: J Virol doi: 10.1128/JVI.01933-06 – volume: 12 start-page: 673 year: 2014 ident: key-10.3201/eid2504.181016-201903171059-R37 article-title: Orthobunyaviruses: recent genetic and structural insights. publication-title: Nat Rev Microbiol doi: 10.1038/nrmicro3332 – volume: 27 start-page: 1219 year: 1981 ident: key-10.3201/eid2504.181016-201903171059-R20 article-title: Antibodies to the California group of arboviruses in the moose (Alces alces americana Clinton) population of Nova Scotia. publication-title: Can J Microbiol doi: 10.1139/m81-187 – volume: 74 start-page: 1078 year: 2006 ident: key-10.3201/eid2504.181016-201903171059-R36 article-title: Seroprevalence and distribution of Flaviviridae, Togaviridae, and Bunyaviridae arboviral infections in rural Cameroonian adults. publication-title: Am J Trop Med Hyg doi: 10.4269/ajtmh.2006.74.1078 – ident: key-10.3201/eid2504.181016-201903171059-R4 – volume: 4 start-page: ofx150 year: 2017 ident: key-10.3201/eid2504.181016-201903171059-R6 article-title: Snowshoe hare virus causing meningoencephalitis in a young adult from northern Manitoba, Canada. publication-title: Open Forum Infect Dis doi: 10.1093/ofid/ofx150 – volume: 22 start-page: 257 year: 2016 ident: key-10.3201/eid2504.181016-201903171059-R9 article-title: Four emerging arboviral diseases in North America: Jamestown Canyon, Powassan, chikungunya, and Zika virus diseases. publication-title: J Neurovirol doi: 10.1007/s13365-016-0428-5 – volume: 92 start-page: 377 year: 2015 ident: key-10.3201/eid2504.181016-201903171059-R19 article-title: Arboviruses in North Dakota, 2003-2006. publication-title: Am J Trop Med Hyg doi: 10.4269/ajtmh.14-0291 – volume: 179 start-page: 783 year: 2011 ident: key-10.3201/eid2504.181016-201903171059-R42 article-title: TLR7 and TLR9 trigger distinct neuroinflammatory responses in the CNS. publication-title: Am J Pathol doi: 10.1016/j.ajpath.2011.04.011 – volume: 35 start-page: 1285 year: 1986 ident: key-10.3201/eid2504.181016-201903171059-R16 article-title: Virus-vector-host relationships of Aedes stimulans and Jamestown Canyon virus in a northern Indiana enzootic focus. publication-title: Am J Trop Med Hyg doi: 10.4269/ajtmh.1986.35.1285 – volume: 198 start-page: 3526 year: 2017 ident: key-10.3201/eid2504.181016-201903171059-R43 article-title: Adaptive immune responses to Zika virus are important for controlling virus infection and preventing infection in brain and testes. publication-title: J Immunol doi: 10.4049/jimmunol.1601949 – volume: 40 start-page: 428 year: 1989 ident: key-10.3201/eid2504.181016-201903171059-R24 article-title: Prevalence of neutralizing antibodies against California and Bunyamwera serogroup viruses in deer from mountainous areas of California. publication-title: Am J Trop Med Hyg doi: 10.4269/ajtmh.1989.40.428 – volume: 33 start-page: 1218 year: 1984 ident: key-10.3201/eid2504.181016-201903171059-R27 article-title: California serogroup viruses in New York State: the role of subtypes in human infections. publication-title: Am J Trop Med Hyg doi: 10.4269/ajtmh.1984.33.1218 – volume: 41 start-page: 117 year: 2015 ident: key-10.3201/eid2504.181016-201903171059-R1 article-title: Emerging mosquito-borne bunyaviruses in Canada. publication-title: Can Commun Dis Rep doi: 10.14745/ccdr.v41i06a01 – volume: 13 start-page: 738 year: 1964 ident: key-10.3201/eid2504.181016-201903171059-R34 article-title: Antibodies in man against Tahyna and Lumbo viruses determined by hemagglutination-inhibition and tissue-culture neutralization tests. publication-title: Am J Trop Med Hyg doi: 10.4269/ajtmh.1964.13.738 – volume: 23 start-page: 588 year: 1986 ident: key-10.3201/eid2504.181016-201903171059-R15 article-title: An ecological study of Jamestown Canyon virus on the Delmarva Peninsula, with emphasis on its possible vector. publication-title: J Med Entomol doi: 10.1093/jmedent/23.6.588 – volume: 5 start-page: 25 year: 2008 ident: key-10.3201/eid2504.181016-201903171059-R44 article-title: La Crosse virus infectivity, pathogenesis, and immunogenicity in mice and monkeys. publication-title: Virol J doi: 10.1186/1743-422X-5-25 – volume: 149 start-page: 119 year: 2010 ident: key-10.3201/eid2504.181016-201903171059-R7 article-title: Nucleotide variability of Tahyna virus (Bunyaviridae, Orthobunyavirus) small (S) and medium (M) genomic segments in field strains differing in biological properties. publication-title: Virus Res doi: 10.1016/j.virusres.2010.01.005 – volume: 16 start-page: 191 year: 2016 ident: key-10.3201/eid2504.181016-201903171059-R10 article-title: Serological survey for antibodies to mosquito-borne bunyaviruses among US National Park Service and US Forest Service employees. publication-title: Vector Borne Zoonotic Dis doi: 10.1089/vbz.2015.1865 – volume: 4 start-page: e6145 year: 2009 ident: key-10.3201/eid2504.181016-201903171059-R14 article-title: The incidence risk, clustering, and clinical presentation of La Crosse virus infections in the eastern United States, 2003-2007. publication-title: PLoS One doi: 10.1371/journal.pone.0006145 – volume: 88 start-page: 11070 year: 2014 ident: key-10.3201/eid2504.181016-201903171059-R39 article-title: Age-dependent myeloid dendritic cell responses mediate resistance to la crosse virus-induced neurological disease. publication-title: J Virol doi: 10.1128/JVI.01866-14 – volume: 6 start-page: 461 year: 1990 ident: key-10.3201/eid2504.181016-201903171059-R18 article-title: Isolation of Jamestown Canyon virus (California serogroup) from Aedes mosquitoes in an enzootic focus in Michigan. publication-title: J Am Mosq Control Assoc – volume: 8 start-page: 136 year: 2011 ident: key-10.3201/eid2504.181016-201903171059-R41 article-title: The full genome sequence of three strains of Jamestown Canyon virus and their pathogenesis in mice or monkeys. publication-title: Virol J doi: 10.1186/1743-422X-8-136 |
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| SubjectTerms | Age Factors Animals Antigens Biochemistry brain Cell death Cells, Cultured Cluster Analysis Comparative analysis Differences in Neuropathogenesis of Encephalitic California Serogroup Viruses disease Disease Models, Animal Encephalitis Virus, California - classification Encephalitis Virus, California - genetics Encephalitis Virus, California - pathogenicity Encephalitis, California - diagnosis Encephalitis, California - epidemiology Encephalitis, California - virology Genes, Viral Geography, Medical Global Health Humans Incidence Mice Nervous system diseases orthobunyaviruses pathogenicity Public Health Surveillance Sequence Analysis, DNA Serogroup susceptibility Viral antigens virus replication |
| Title | Differences in Neuropathogenesis of Encephalitic California Serogroup Viruses |
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