Using machine learning on cardiorespiratory fitness data for predicting hypertension: The Henry Ford ExercIse Testing (FIT) Project

This study evaluates and compares the performance of different machine learning techniques on predicting the individuals at risk of developing hypertension, and who are likely to benefit most from interventions, using the cardiorespiratory fitness data. The dataset of this study contains information...

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Bibliographic Details
Published in:PloS one Vol. 13; no. 4; p. e0195344
Main Authors: Sakr, Sherif, Elshawi, Radwa, Ahmed, Amjad, Qureshi, Waqas T., Brawner, Clinton, Keteyian, Steven, Blaha, Michael J., Al-Mallah, Mouaz H.
Format: Journal Article
Language:English
Published: United States Public Library of Science 18.04.2018
Public Library of Science (PLoS)
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ISSN:1932-6203, 1932-6203
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Summary:This study evaluates and compares the performance of different machine learning techniques on predicting the individuals at risk of developing hypertension, and who are likely to benefit most from interventions, using the cardiorespiratory fitness data. The dataset of this study contains information of 23,095 patients who underwent clinician- referred exercise treadmill stress testing at Henry Ford Health Systems between 1991 and 2009 and had a complete 10-year follow-up. The variables of the dataset include information on vital signs, diagnosis and clinical laboratory measurements. Six machine learning techniques were investigated: LogitBoost (LB), Bayesian Network classifier (BN), Locally Weighted Naive Bayes (LWB), Artificial Neural Network (ANN), Support Vector Machine (SVM) and Random Tree Forest (RTF). Using different validation methods, the RTF model has shown the best performance (AUC = 0.93) and outperformed all other machine learning techniques examined in this study. The results have also shown that it is critical to carefully explore and evaluate the performance of the machine learning models using various model evaluation methods as the prediction accuracy can significantly differ.
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Competing Interests: The authors have declared that no competing interests exist.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0195344