The many faces of ubiquitinated histone H2A: insights from the DUBs

Monoubiquitination of H2A is a major histone modification in mammalian cells. Understanding how monoubiquitinated H2A (uH2A) regulates DNA-based processes in the context of chromatin is a challenging question. Work in the past years linked uH2A to transcriptional repression by the Polycomb group pro...

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Bibliographic Details
Published in:Cell division Vol. 3; no. 1; p. 8
Main Authors: Vissers, Joseph HA, Nicassio, Francesco, van Lohuizen, Maarten, Di Fiore, Pier Paolo, Citterio, Elisabetta
Format: Journal Article
Language:English
Published: London BioMed Central 22.04.2008
BMC
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ISSN:1747-1028, 1747-1028
Online Access:Get full text
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