Perioperative cancer cell dissemination detected with a real-time RT-PCR assay for EpCAM is not associated with worse prognosis in pancreatic ductal adenocarcinoma

Background Epithelial cell adhesion molecule (EpCAM) has been used as surrogate marker for the quantification of circulating tumour cells (CTC). Our aim was to prospectively study the value of a real-time RT-PCR assay for EpCAM detection in the peripheral blood and peritoneal cavity of patients unde...

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Vydáno v:	BMC cancer Ročník 11; číslo 1; s. 47
Hlavní autoři:	Sergeant, Gregory, Roskams, Tania, van Pelt, Jos, Houtmeyers, François, Aerts, Raymond, Topal, Baki
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	London BioMed Central 31.01.2011 BioMed Central Ltd Springer Nature B.V BMC
Témata:	Adenocarcinoma - diagnosis Adenocarcinoma - genetics Adenocarcinoma - pathology Adenocarcinoma - surgery Aged Antigens, Neoplasm - blood Antigens, Neoplasm - genetics Antigens, Neoplasm - metabolism Ascitic Fluid - metabolism Ascitic Fluid - pathology Biomarkers, Tumor - blood Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Biomedical and Life Sciences Biomedicine Blood Cancer cells Cancer Research Carcinoma, Pancreatic Ductal - diagnosis Carcinoma, Pancreatic Ductal - genetics Carcinoma, Pancreatic Ductal - pathology Carcinoma, Pancreatic Ductal - surgery Cell adhesion & migration Cell adhesion molecules Cell Adhesion Molecules - blood Cell Adhesion Molecules - genetics Cell Adhesion Molecules - metabolism Clinical oncology Computer Systems Epithelial Cell Adhesion Molecule Female Health Promotion and Disease Prevention Hepatology Hospitals Humans Immune system Male Medicine/Public Health Middle Aged Neoplastic Cells, Circulating - metabolism Neoplastic Cells, Circulating - pathology Oncology Pancreatectomy Pancreatic cancer Pancreatic Neoplasms - diagnosis Pancreatic Neoplasms - genetics Pancreatic Neoplasms - pathology Pancreatic Neoplasms - surgery Pathology Perioperative Period - adverse effects Peritoneal Lavage Physiological aspects Polymerase chain reaction Postoperative period Predictive Value of Tests Prognosis Research Article Reverse Transcriptase Polymerase Chain Reaction - methods Studies Surgery Surgical Oncology Peritoneal Lavage Chronic Pancreatitis Circulate Tumour Cell Pancreatic Ductal Adenocarcinoma Disseminate Tumour Cell
ISSN:	1471-2407, 1471-2407
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