Identification and proteomic profiling of exosomes in human cerebrospinal fluid

Background Exosomes are released from multiple cell types, contain protein and RNA species, and have been exploited as a novel reservoir for disease biomarker discovery. They can transfer information between cells and may cause pathology, for example, a role for exosomes has been proposed in the pat...

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Veröffentlicht in:	Journal of translational medicine Jg. 10; H. 1; S. 5
Hauptverfasser:	Street, Jonathan M, Barran, Perdita E, Mackay, C Logan, Weidt, Stefan, Balmforth, Craig, Walsh, Tim S, Chalmers, Rod TA, Webb, David J, Dear, James W
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London BioMed Central 05.01.2012 BioMed Central Ltd Springer Nature B.V BMC
Schlagworte:	Aged Alzheimer's disease Biological markers Biomarkers Biomedical and Life Sciences Biomedicine Cellular proteins Cerebrospinal fluid Cerebrospinal Fluid - metabolism CSF Cyclotrons Demography Exosomes Exosomes - metabolism Exosomes - ultrastructure Fluorides Fourier Analysis Fourier transforms human Humans Ions Male Mass Spectrometry Medicine/Public Health Molecular weight Neuroscience Physiological aspects Proteins proteomics Proteomics - methods Studies Ultracentrifugation United Kingdom proteomics Exosomes human CSF
ISSN:	1479-5876, 1479-5876
Online-Zugang:	Volltext
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