Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial

A recombinant, replication-competent vesicular stomatitis virus-based vaccine expressing a surface glycoprotein of Zaire Ebolavirus (rVSV-ZEBOV) is a promising Ebola vaccine candidate. We report the results of an interim analysis of a trial of rVSV-ZEBOV in Guinea, west Africa. For this open-label,...

Full description

Saved in:

Bibliographic Details
Published in:	The Lancet (British edition) Vol. 386; no. 9996; pp. 857 - 866
Main Authors:	Henao-Restrepo, Ana Maria, Longini, Ira M, Egger, Matthias, Dean, Natalie E, Edmunds, W John, Camacho, Anton, Carroll, Miles W, Doumbia, Moussa, Draguez, Bertrand, Duraffour, Sophie, Enwere, Godwin, Grais, Rebecca, Gunther, Stephan, Hossmann, Stefanie, Kondé, Mandy Kader, Kone, Souleymane, Kuisma, Eeva, Levine, Myron M, Mandal, Sema, Norheim, Gunnstein, Riveros, Ximena, Soumah, Aboubacar, Trelle, Sven, Vicari, Andrea S, Watson, Conall H, Kéïta, Sakoba, Kieny, Marie Paule, Røttingen, John-Arne
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 29.08.2015 Elsevier Limited
Subjects:	Adult Breast feeding Clinical trials Ebola Vaccines Ebola virus Ebolavirus - immunology Female Genetic Vectors Glycoproteins Guinea - epidemiology Hemorrhagic Fever, Ebola - epidemiology Hemorrhagic Fever, Ebola - prevention & control Humans Immunization Incidence Internal Medicine Kaplan-Meier Estimate Male Membrane Glycoproteins - metabolism Middle Aged Public health Vaccination - methods Vaccines Vesiculovirus - metabolism Young Adult Guinea Africa
ISSN:	0140-6736, 1474-547X
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!