Evolutionary enhancement of Zika virus infectivity in Aedes aegypti mosquitoes

A mutation that increases the secretion of Zika virus non-structural protein 1 (NS1) in infected hosts enhances the ability of the virus to infect its mosquito vector Aedes aegypti and might have contributed to the recent Zika epidemic. Mutation enhances Zika infectivity in mosquitoes Several flaviv...

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Veröffentlicht in:	Nature (London) Jg. 545; H. 7655; S. 482 - 486
Hauptverfasser:	Liu, Yang, Liu, Jianying, Du, Senyan, Shan, Chao, Nie, Kaixiao, Zhang, Rudian, Li, Xiao-Feng, Zhang, Renli, Wang, Tao, Qin, Cheng-Feng, Wang, Penghua, Shi, Pei-Yong, Cheng, Gong
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 25.05.2017 Nature Publishing Group
Schlagworte:	38/109 38/77 38/90 631/326/596/2563 64/60 692/420/254 82/83 Aedes - virology Americas - epidemiology Amino Acid Sequence Amino Acid Substitution Animals Asia - epidemiology Biological Evolution Cambodia - epidemiology Female Genetic aspects Health aspects Humanities and Social Sciences Humans letter Life Cycle Stages Mice Mice, Inbred C57BL Mosquito Vectors - virology multidisciplinary Phylogeny Science Vero Cells Viral Nonstructural Proteins - chemistry Viral Nonstructural Proteins - genetics Viral Nonstructural Proteins - metabolism Yellow fever mosquito Zika virus Zika Virus - genetics Zika Virus - isolation & purification Zika Virus - metabolism Zika Virus - pathogenicity Zika Virus Infection - epidemiology Zika Virus Infection - transmission Zika Virus Infection - virology
ISSN:	0028-0836, 1476-4687, 1476-4687
Online-Zugang:	Volltext
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