Effect of Folic Acid Fortification on Plasma Folate and Total Homocysteine Concentrations

Background In 1996, the Food and Drug Administration issued a regulation requiring all enriched grain products to be fortified with folic acid to reduce the risk of neural-tube defects in newborns. Fortification (140 μg per 100 g) began in 1996, and the process was essentially complete by mid-1997....

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Bibliographic Details
Published in:	The New England journal of medicine Vol. 340; no. 19; pp. 1449 - 1454
Main Authors:	Jacques, P.F, Selhub, J, Bostom, A.G, Wilson, P.W.F, Rosenberg, I.H
Format:	Journal Article
Language:	English
Published:	Boston, MA Massachusetts Medical Society 13.05.1999
Subjects:	Acids Adult Age Aged Aged, 80 and over Biological and medical sciences Birth defects blood plasma Case-Control Studies Cohort Studies Dietary Supplements Federal regulation Female folic acid Folic Acid - administration & dosage Folic Acid - blood Folic Acid Deficiency - drug therapy food fortification Food, Fortified General and cellular metabolism. Vitamins hematologic tests homocysteine Homocysteine - blood human health human nutrition Humans Male Medical sciences Middle age Middle Aged Older people Pharmacology. Drug treatments Vitamin B Vitamin B Complex - administration & dosage Womens health Human Plasma Middle age Hematology Vitamin Biological marker Marker Concentration Epidemiology Folic acid Folate Cohort study Total Biological effect Effectiveness factor Elderly
ISSN:	0028-4793, 1533-4406
Online Access:	Get full text
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