A stochastic spectral analysis of transcriptional regulatory cascades

The past decade has seen great advances in our understanding of the role of noise in gene regulation and the physical limits to signaling in biological networks. Here, we introduce the spectral method for computation of the joint probability distribution over all species in a biological network. The...

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Vydané v:	Proceedings of the National Academy of Sciences - PNAS Ročník 106; číslo 16; s. 6529
Hlavní autori:	Walczak, Aleksandra M, Mugler, Andrew, Wiggins, Chris H
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 21.04.2009
Predmet:	Computational Biology - methods Down-Regulation Gene Expression Regulation Signal Transduction - genetics Stochastic Processes Transcription, Genetic Up-Regulation
ISSN:	1091-6490, 1091-6490
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