A stochastic spectral analysis of transcriptional regulatory cascades

The past decade has seen great advances in our understanding of the role of noise in gene regulation and the physical limits to signaling in biological networks. Here, we introduce the spectral method for computation of the joint probability distribution over all species in a biological network. The...

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Bibliographic Details

Published in:	Proceedings of the National Academy of Sciences - PNAS Vol. 106; no. 16; p. 6529
Main Authors:	Walczak, Aleksandra M, Mugler, Andrew, Wiggins, Chris H
Format:	Journal Article
Language:	English
Published:	United States 21.04.2009
Subjects:	Computational Biology - methods Down-Regulation Gene Expression Regulation Signal Transduction - genetics Stochastic Processes Transcription, Genetic Up-Regulation
ISSN:	1091-6490, 1091-6490
Online Access:	Get more information
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