Metabolomics profiling in hypertension and blood pressure regulation: a review

Hypertension is a chronic health condition in which blood pressure is usually elevated beyond normal levels. It can progress with serious complications if left undetected and untreated. Incidence of hypertension is on the increase worldwide with debilitating consequences on the health systems of man...

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Vydáno v:Clinical hypertension Ročník 26; číslo 1; s. 1 - 8
Hlavní autoři: Onuh, John O., Aliani, Michel
Médium: Journal Article
Jazyk:angličtina
Vydáno: London BioMed Central 15.11.2020
BioMed Central Ltd
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Témata:
Age
Aliskiren
Amino acids
Angiology
Angiotensin II
Antihypertensives
Biomarkers
Blood pressure
Cardiology
Developing countries
Hypertension
Investigations
LDCs
Medical research
Medicine
Medicine & Public Health
Metabolism
Metabolites
Metabolomics
Oxidative stress
Pathways
Review
내과학
Hypertension
Biomarkers
Metabolomics
Pathways
Metabolites
ISSN:2056-5909, 1342-2154, 2635-6325, 2056-5909
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Popis
Shrnutí:Hypertension is a chronic health condition in which blood pressure is usually elevated beyond normal levels. It can progress with serious complications if left undetected and untreated. Incidence of hypertension is on the increase worldwide with debilitating consequences on the health systems of many countries. It is a multifactorial disorder that requires a multi-pronged approach to address it. One such approach is the use of metabolomics or metabolite profiling to understand its underlying cause and possibly control it. Changes in metabolites profiles have been used to accurately predict so many disease conditions in addition to identifying possible biomarkers and pathways associated in their pathogenicity. This will enable their early detection, diagnosis and treatment as well as likely complications that may arise and also assist in development of biomarkers for clinical uses. The objective of this review therefore is to present some of the current knowledge on the application of metabolomics profiling in hypertension and blood pressure control.
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https://clinicalhypertension.biomedcentral.com/articles/10.1186/s40885-020-00157-9
ISSN:2056-5909
1342-2154
2635-6325
2056-5909
DOI:10.1186/s40885-020-00157-9