The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice

Polygenic risk score analyses on embryos (PGT-P) are being marketed by some private testing companies to parents using in vitro fertilisation as being useful in selecting the embryos that carry the least risk of disease in later life. It appears that at least one child has been born after such a pro...

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Bibliographic Details
Published in:	European journal of human genetics : EJHG Vol. 30; no. 5; pp. 493 - 495
Main Authors:	Forzano, Francesca, Antonova, Olga, Clarke, Angus, de Wert, Guido, Hentze, Sabine, Jamshidi, Yalda, Moreau, Yves, Perola, Markus, Prokopenko, Inga, Read, Andrew, Reymond, Alexandre, Stefansdottir, Vigdis, van El, Carla, Genuardi, Maurizio
Format:	Journal Article
Language:	English
Published:	England Nature Publishing Group 01.05.2022
Subjects:	Alzheimer's disease Embryos Estimates Fertilization Genetic Predisposition to Disease Genetic screening Genetic Testing Genetics Genome-Wide Association Study Humans In vitro fertilization Medicine Minority & ethnic groups Multifactorial Inheritance Parents & parenting Polygenic inheritance Population Prenatal development Risk assessment Risk Factors
ISSN:	1018-4813, 1476-5438, 1476-5438
Online Access:	Get full text
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