Nonalcoholic fatty liver disease (NAFLD) from pathogenesis to treatment concepts in humans

Nonalcoholic fatty liver disease (NAFLD) comprises hepatic alterations with increased lipid accumulation (steatosis) without or with inflammation (nonalcoholic steatohepatitis, NASH) and/or fibrosis in the absence of other causes of liver disease. NAFLD is developing as a burgeoning health challenge...

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Bibliographic Details
Published in:	Molecular metabolism (Germany) Vol. 50; p. 101122
Main Authors:	Pafili, Kalliopi, Roden, Michael
Format:	Journal Article
Language:	English
Published:	Germany Elsevier GmbH 01.08.2021 Elsevier
Subjects:	Adipocytes - metabolism Clinical trials Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - drug therapy Diabetes Mellitus, Type 2 - metabolism Disease Progression Fatty Acids - metabolism Fatty liver Fibrosis Genetic Predisposition to Disease Genetic Variation Humans Inflammation Insulin Resistance Lipid Metabolism - drug effects Lipotoxicity Liver - cytology Liver - pathology Mitochondria - pathology Non-alcoholic Fatty Liver Disease - drug therapy Non-alcoholic Fatty Liver Disease - etiology Non-alcoholic Fatty Liver Disease - metabolism Non-alcoholic Fatty Liver Disease - pathology Obesity - complications Obesity - drug therapy Obesity - metabolism Oxidative Stress - drug effects Polymorphism, Single Nucleotide Review Clinical trials Insulin resistance Inflammation Fatty liver Lipotoxicity Fibrosis
ISSN:	2212-8778, 2212-8778
Online Access:	Get full text
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