Menopause accelerates biological aging

Although epigenetic processes have been linked to aging and disease in other systems, it is not yet known whether they relate to reproductive aging. Recently, we developed a highly accurate epigenetic biomarker of age (known as the "epigenetic clock"), which is based on DNA methylation lev...

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Bibliographic Details

Published in:	Proceedings of the National Academy of Sciences - PNAS Vol. 113; no. 33; p. 9327
Main Authors:	Levine, Morgan E, Lu, Ake T, Chen, Brian H, Hernandez, Dena G, Singleton, Andrew B, Ferrucci, Luigi, Bandinelli, Stefania, Salfati, Elias, Manson, JoAnn E, Quach, Austin, Kusters, Cynthia D J, Kuh, Diana, Wong, Andrew, Teschendorff, Andrew E, Widschwendter, Martin, Ritz, Beate R, Absher, Devin, Assimes, Themistocles L, Horvath, Steve
Format:	Journal Article
Language:	English
Published:	United States 16.08.2016
Subjects:	Adult Aging - physiology Epigenesis, Genetic Female Humans Mendelian Randomization Analysis Menopause - physiology Middle Aged Ovariectomy Polymorphism, Single Nucleotide DNA methylation WHI aging menopause epigenetic clock
ISSN:	1091-6490, 1091-6490
Online Access:	Get more information
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