Menopause accelerates biological aging

Although epigenetic processes have been linked to aging and disease in other systems, it is not yet known whether they relate to reproductive aging. Recently, we developed a highly accurate epigenetic biomarker of age (known as the "epigenetic clock"), which is based on DNA methylation lev...

Celý popis

Podrobná bibliografie

Vydáno v:	Proceedings of the National Academy of Sciences - PNAS Ročník 113; číslo 33; s. 9327
Hlavní autoři:	Levine, Morgan E, Lu, Ake T, Chen, Brian H, Hernandez, Dena G, Singleton, Andrew B, Ferrucci, Luigi, Bandinelli, Stefania, Salfati, Elias, Manson, JoAnn E, Quach, Austin, Kusters, Cynthia D J, Kuh, Diana, Wong, Andrew, Teschendorff, Andrew E, Widschwendter, Martin, Ritz, Beate R, Absher, Devin, Assimes, Themistocles L, Horvath, Steve
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 16.08.2016
Témata:	Adult Aging - physiology Epigenesis, Genetic Female Humans Mendelian Randomization Analysis Menopause - physiology Middle Aged Ovariectomy Polymorphism, Single Nucleotide DNA methylation WHI aging menopause epigenetic clock
ISSN:	1091-6490, 1091-6490
On-line přístup:	Zjistit podrobnosti o přístupu
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!