Epidermal Cell Fate Determination in Arabidopsis: Patterns Defined by a Steroid-Inducible Regulator

The Arabidopsis mutant ttg lacks both trichomes (epidermal hairs) and anthocyanin pigments. Trichomes and anthocyanins are restored by the constitutive expression of the maize transcriptional regulator (R). The expression of an R-glucocorticoid receptor chimeric protein results in a steroid hormone-...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) Jg. 266; H. 5184; S. 436 - 439
Hauptverfasser:	Lloyd, Alan M., Schena, Mark, Walbot, Virginia, Davis, Ronald W.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Washington, DC American Society for the Advancement of Science 21.10.1994 American Association for the Advancement of Science
Schlagworte:	Alleles Amino acids Anthocyanins - biosynthesis Anthocyanins - genetics Arabidopsis Arabidopsis - cytology Arabidopsis - genetics Arabidopsis - growth & development Arabidopsis - metabolism Biological and medical sciences Cell differentiation Cell physiology Cell regulation Cellular control mechanisms Dexamethasone - pharmacology Epidermal cells Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Plant Hormones Leaves Microscopy, Electron, Scanning Pigments Plant cells Plant Leaves - cytology Plant Leaves - growth & development Plant Leaves - ultrastructure Plant physiology and development Receptors, Glucocorticoid - physiology Recombinant Fusion Proteins Regulator genes Seedlings Steroids Trans-Activators - physiology Transformation, Genetic Trichomes Anthocyanin Biosynthesis Determination Gene expression Trichome Arabidopsis thaliana Cruciferae Dicotyledones Angiospermae Hormonal regulation Pigments Development Spermatophyta Differentiation Hybrid gene
ISSN:	0036-8075, 1095-9203
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Abstract	The Arabidopsis mutant ttg lacks both trichomes (epidermal hairs) and anthocyanin pigments. Trichomes and anthocyanins are restored by the constitutive expression of the maize transcriptional regulator (R). The expression of an R-glucocorticoid receptor chimeric protein results in a steroid hormone-dependent, conditional allele of R that functions in whole Arabidopsis plants. The response of the chimeric protein to pulses of hormone was used to define the pattern and timing of trichome formation on the developing leaf epidermis. Each adaxial epidermal leaf cell appears to have an equal probability of differentiating into a trichome; there is a temporal zone of decision for trichome cell fate that proceeds as a wave from the tip to the base of developing leaves.
AbstractList	The Arabidopsis mutant ttg lacks both trichomes (epidermal hairs) and anthocyanin pigments. Trichomes and anthocyanins are restored by the constitutive expression of the maize transcriptional regulator (R). The expression of an R-glucocorticoid receptor chimeric protein results in a steroid hormone-dependent, conditional allele of R that functions in whole Arabidopsis plants. The response of the chimeric protein to pulses of hormone was used to define the pattern and timing of trichome formation on the developing leaf epidermis. Each adaxial epidermal leaf cell appears to have an equal probability of differentiating into a trichome; there is a temporal zone of decision for trichome cell fate that proceeds as a wave from the tip to the base of developing leaves. The Arabidopsis mutant ttg lacks both trichomes (epidermal hairs) and anthocyanin pigments. Trichomes and anthocyanins are restored by the constitutive expression of the maize transcriptional regulator (R). The expression of an R-glucocorticoid receptor chimeric protein results in a steroid hormone-dependent, conditional allele of R that functions in whole Arabidopsis plants. The response of the chimeric protein to pulses of hormone was used to define the pattern and timing of trichome formation on the developing leaf epidermis. Each adaxial epidermal leaf cell appears to have an equal probability of differentiating into a trichome; there is a temporal zone of decision for trichome cell fate that proceeds as a wave from the tip to the base of developing leaves. The Arabidopsis mutant ttg lacks both trichomes (epidermal hairs) and anthocyanin pigments. Trichomes and anthocyanins are restored by the constitutive expression of the maize transcriptional regulator (R). The expression of an R-glucocorticoid receptor chimeric protein results in a steroid hormone-dependent, conditional allele of R that functions in whole Arabidopsis plants. The response of the chimeric protein to pulses of hormone was used to define the pattern and timing of trichome formation on the developing leaf epidermis. Each adaxial epidermal leaf cell appears to have an equal probability of differentiating into a trichome; there is a temporal zone of decision for trichome cell fate that proceeds as a wave from the tip to the base of developing leaves.The Arabidopsis mutant ttg lacks both trichomes (epidermal hairs) and anthocyanin pigments. Trichomes and anthocyanins are restored by the constitutive expression of the maize transcriptional regulator (R). The expression of an R-glucocorticoid receptor chimeric protein results in a steroid hormone-dependent, conditional allele of R that functions in whole Arabidopsis plants. The response of the chimeric protein to pulses of hormone was used to define the pattern and timing of trichome formation on the developing leaf epidermis. Each adaxial epidermal leaf cell appears to have an equal probability of differentiating into a trichome; there is a temporal zone of decision for trichome cell fate that proceeds as a wave from the tip to the base of developing leaves.
Audience	Academic
Author	Schena, Mark Walbot, Virginia Lloyd, Alan M. Davis, Ronald W.
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Keywords	Anthocyanin Biosynthesis Determination Gene expression Trichome Arabidopsis thaliana Cruciferae Dicotyledones Angiospermae Hormonal regulation Pigments Development Spermatophyta Differentiation Hybrid gene
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References	(e_1_2_1_22_1) 1988; 54 (e_1_2_1_17_1) 1989; 86 (e_1_2_1_25_1) 1991; 3 (e_1_2_1_5_1) 1994; 166 (e_1_2_1_8_1) 1993; 90 (e_1_2_1_19_1) 1986; 46 (e_1_2_1_2_1) 1992; 8 (e_1_2_1_24_1) 1993; 5 (e_1_2_1_32_1) 1988; 147 (e_1_2_1_28_1) 1991; 88 (e_1_2_1_14_1) 1993; 5 e_1_2_1_29_1 (e_1_2_1_11_1) 1981; 18 (e_1_2_1_1_1) 1989; 8 (e_1_2_1_10_1) 1994; 76 (e_1_2_1_31_1) 1988; 85 (e_1_2_1_6_1) 1992; 6 (e_1_2_1_9_1) 1990; 87 (e_1_2_1_33_1) 1991; 5 (e_1_2_1_27_1) 1987; 61 (e_1_2_1_3_1) 1981; 33 (e_1_2_1_21_1) 1991; 67 (e_1_2_1_4_1) 1989; 340 (e_1_2_1_26_1) 1970; 52 (e_1_2_1_12_1) 1990; 27 (e_1_2_1_13_1) 1981; 88 e_1_2_1_16_1 (e_1_2_1_20_1) 1990; 4 (e_1_2_1_23_1) 1992; 13 (e_1_2_1_30_1) 1991; 88 e_1_2_1_15_1 (e_1_2_1_7_1) 1991; 13 e_1_2_1_18_1
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Snippet	The Arabidopsis mutant ttg lacks both trichomes (epidermal hairs) and anthocyanin pigments. Trichomes and anthocyanins are restored by the constitutive... The Arabidopsis mutant ttg lacks both trichomes (epidermal hairs) and anthocyanin pigments. Trichomes and anthocyanins are restored by the constitutive...
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SubjectTerms	Alleles Amino acids Anthocyanins - biosynthesis Anthocyanins - genetics Arabidopsis Arabidopsis - cytology Arabidopsis - genetics Arabidopsis - growth & development Arabidopsis - metabolism Biological and medical sciences Cell differentiation Cell physiology Cell regulation Cellular control mechanisms Dexamethasone - pharmacology Epidermal cells Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Plant Hormones Leaves Microscopy, Electron, Scanning Pigments Plant cells Plant Leaves - cytology Plant Leaves - growth & development Plant Leaves - ultrastructure Plant physiology and development Receptors, Glucocorticoid - physiology Recombinant Fusion Proteins Regulator genes Seedlings Steroids Trans-Activators - physiology Transformation, Genetic Trichomes
Title	Epidermal Cell Fate Determination in Arabidopsis: Patterns Defined by a Steroid-Inducible Regulator
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