Cataloging Existing Hearing Loss Cohort Data to Guide the Development of Precision Medicine for Sensorineural Hearing Loss: A Systematic Review of Hearing Repositories

Recent breakthroughs in our understanding of sensorineural hearing loss etiology have encouraged the identification of novel hearing therapeutics, paving the way for precision hearing medicine. Critical to this field is the curation of health resources on hearing data. A systematic review of the lit...

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Bibliographic Details
Published in:Journal of International Advanced Otology Vol. 19; no. 5; pp. 420 - 425
Main Authors: Sethukumar, Priya, Mandavia, Rishi, Yildirim, Omursen, Hazell, Georgina, Devakumar, Haran, Ahmed, Muhammad, Stragier, Emilien, Duran, Marie Josée, Schilder, Anne G.M., Mehta, Nishchay
Format: Journal Article
Language:English
Published: Turkey AVES 01.09.2023
AVES Yayincilik A.S
Mediterranean Society for Otology and Audiology
European Academy of Otology and Neurotology and the Politzer Society
European Academy of Otology & Neuro-Otology
Subjects:
Adults
Cardiovascular diseases
Datasets
Deafness
Dementia disorders
Demographics
Development and progression
Economic impact
Global health
Grey literature
Health insurance
Hearing
Hearing Loss
Hearing Loss, Sensorineural - diagnosis
Hearing Loss, Sensorineural - genetics
Hearing Loss, Sensorineural - therapy
Hearing protection
Homeopathy
Humans
Literature reviews
Materia medica and therapeutics
Medical screening
Pediatrics
Physical instruments
Population
Precision Medicine
Quality of life
Review
Search strategies
Systematic review
Therapeutics
United Kingdom
United Kingdom > UK
ISSN:2148-3817, 1308-7649, 2148-3817
Online Access:Get full text
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Description
Summary:Recent breakthroughs in our understanding of sensorineural hearing loss etiology have encouraged the identification of novel hearing therapeutics, paving the way for precision hearing medicine. Critical to this field is the curation of health resources on hearing data. A systematic review of the literature was conducted to map existing (inter)national and regional datasets that include hearing data to inform the development of future hearing repositories. Systematic literature review was performed adhering to Preferred Reporting Items for Systematic Review and MetaAnalysis recommendations. Databases, including those from gray literature, were searched to identify publications reporting on phenotypic and/ or genotypic hearing data in May 2019. The databases reviewed were Medline, PubMed, Embase databases, and Google Scholar. Publications on local datasets were excluded. All hearing datasets identified in the screening process were noted. For each dataset, geography, context, objective, period of time run, numbers and demographics of participants, genomic data, hearing measures and instruments used were extracted and cataloged. One hundred and eighty-eight datasets were identified, containing hearing data on populations ranging from 100 to 1.39 million individuals, and all extracted data have been cataloged. This searchable resource has been made accessible online. This unique catalog provides an overview of existing datasets that contain valuable information on hearing. This can be used to inform the development of national and international patient data repositories for hearing loss and guide strategic collaboration between key stakeholder groups, pivotal to the delivery and development of sensorineural hearing loss precision diagnostics and treatments. Cite this article as: Sethukumar P, Mandavia R, Yildirim O, et  al. Cataloging existing hearing loss cohort data to guide the development of precision medicine for sensorineural hearing loss: A systematic review of hearing repositories. J Int Adv Otol. 2023;19(5):420-425.
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This work was presented at International Symposium of Inner Ear Therapeutics, held in Hannover, Germany, 4-6 November 2019, and the workshop “Planning for the implementation of Novel Hearing Therapeutics into Healthcare Systems” at the Association of Research in Otolaryngology virtual meeting, 19 February 2021.
Cite this article as: Sethukumar P, Mandavia R, Yildirim O, et al. Cataloging existing hearing loss cohort data to guide the development of precision medicine for sensorineural hearing loss: A systematic review of hearing repositories. J Int Adv Otol. 2023;19(5):420-425.
ORCID iDs of the authors: P.S. 0000-0002-3325-9313, R.M. 0000-0002-5839-2735, O.Y. 0000-0003-3169-1214, G.H. 0000-0002-8132-7245, H.D. 0000-0002-7918-9189, M.A. 0000-0001-6641-4052, E.S. 0000-0003-2359-6882, M.J.D. 0000-0002-6096-9046, A.G.M.S. 0000-0002-5496-4580, N.M. 0000-0001-9317-3055, M.F. 0000-0002-0753-297X.
ISSN:2148-3817
1308-7649
2148-3817
DOI:10.5152/iao.2023.22690